Literature DB >> 3582134

In vitro antibacterial activity of irloxacin (E-3432) on clinical isolates.

R Coll, M Esteve, M Moros, M A Xicota, J Parés.   

Abstract

Irloxacin (E-3432) is a new quinolone derivative. In this study, the activity of irloxacin was compared with that of nalidixic acid, norfloxacin and ciprofloxacin against strains of clinical isolates. Irloxacin showed greater in vitro activity than nalidixic acid, similar activity to norfloxacin and lower activity than ciprofloxacin. Against Staphylococcus, the MIC range of E-3432 was 0.06-1 mg/l, better than the other compounds studied.

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Year:  1987        PMID： 3582134

Source DB:  PubMed          Journal:  Drugs Exp Clin Res        ISSN： 0378-6501


  8 in total

1.  In vitro and in vivo antibacterial activities of E-4497, a new 3-amine-3-methyl-azetidinyl tricyclic fluoroquinolone.

Authors:  D Gargallo-Viola; M Esteve; S Llovera; X Roca; J Guinea
Journal:  Antimicrob Agents Chemother       Date:  1991-03       Impact factor: 5.191

2.  Comparative in vitro and in vivo activities of six new monofluoroquinolone and difluoroquinolone 3-carboxylic acids with a 7-azetidin ring substituent.

Authors:  D Gargallo-Viola; M Esteve; M Moros; R Coll; M A Xicota; C de Andres; R Roser; J Guinea
Journal:  Antimicrob Agents Chemother       Date:  1990-12       Impact factor: 5.191

3.  In vitro activities of irloxacin and E-3846, two new quinolones.

Authors:  J A García-Rodríguez; J E García Sánchez; J L Muñoz Bellido; I Trujillano
Journal:  Antimicrob Agents Chemother       Date:  1990-06       Impact factor: 5.191

4.  Antibacterial activity and pharmacokinetics of four new 7-azetidinyl fluoroquinolones.

Authors:  R Coll; D Gargallo-Viola; E Tudela; M A Xicota; S Llovera; J Guinea
Journal:  Antimicrob Agents Chemother       Date:  1996-01       Impact factor: 5.191

5.  Antibacterial activities and pharmacokinetics of E-4767 and E-5065, two new 8-chlorofluoroquinolones with a 7-azetidin ring substituent.

Authors:  D Gargallo-Viola; S Ferrer; E Tudela; M Robert; R Coll; R Roser; J Guinea
Journal:  Antimicrob Agents Chemother       Date:  2001-11       Impact factor: 5.191

6.  Activity of E-3846, a new fluoroquinolone, in vitro and in experimental cystitis and pyelonephritis in rats.

Authors:  D Gargallo; M Moros; R Coll; M Esteve; J Parés; M A Xicota; J Guinea
Journal:  Antimicrob Agents Chemother       Date:  1988-05       Impact factor: 5.191

7.  In vitro and in vivo antibacterial activities of E-4868, a new fluoroquinolone with a 7-azetidin ring substituent.

Authors:  J Guinea; M Robert; D Gargallo-Viola; M A Xicota; J Garcia; E Tudela; M Esteve; R Coll; M Pares; R Roser
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

8.  E-4695, a new C-7 azetidinyl fluoronaphthyridine with enhanced activity against gram-positive and anaerobic pathogens.

Authors:  J Guinea; D Gargallo-Viola; M Robert; E Tudela; M A Xicota; J Garcia; M Esteve; R Coll; M Pares; R Roser
Journal:  Antimicrob Agents Chemother       Date:  1995-02       Impact factor: 5.191
  8 in total

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