Literature DB >> 3581712

A comparison of 3 and 6 weeks' anticoagulation in the treatment of venous thromboembolism.

A G Fennerty, J Dolben, P Thomas, G Backhouse, D P Bentley, I A Campbell, P A Routledge.   

Abstract

One hundred hospital in-patients treated for pulmonary embolism (PE) and/or deep vein thrombosis (DVT) were randomly allocated to receive 3 or 6 weeks' anticoagulation with heparin and warfarin. At one year recurrence rates were 12% in the 6 week group and 10% in those treated for 3 weeks. No patient died as a result of recurrence. Our study suggests that 3 weeks' anticoagulation therapy, using intravenous heparin for the first 5 days and warfarin from the third day, is adequate for patients without persisting risk factors.

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Year:  1987        PMID: 3581712     DOI: 10.1111/j.1365-2257.1987.tb01377.x

Source DB:  PubMed          Journal:  Clin Lab Haematol        ISSN: 0141-9854


  6 in total

Review 1.  Anticoagulants in venous thromboembolism.

Authors:  A Fennerty; I A Campbell; P A Routledge
Journal:  BMJ       Date:  1988-11-19

2.  Anticoagulation for three versus six months in patients with deep vein thrombosis or pulmonary embolism, or both: randomised trial.

Authors:  I A Campbell; D P Bentley; R J Prescott; P A Routledge; H G M Shetty; I J Williamson
Journal:  BMJ       Date:  2007-02-08

3.  Clinical evidence for rebound hypercoagulability after discontinuing oral anticoagulants for venous thromboembolism.

Authors:  David Keith Cundiff
Journal:  Medscape J Med       Date:  2008-11-11

Review 4.  Pharmacotherapeutic aspects of unfractionated and low molecular weight heparins.

Authors:  M Verstraete
Journal:  Drugs       Date:  1990-10       Impact factor: 9.546

5.  Influence of preceding length of anticoagulant treatment and initial presentation of venous thromboembolism on risk of recurrence after stopping treatment: analysis of individual participants' data from seven trials.

Authors:  Florent Boutitie; Laurent Pinede; Sam Schulman; Giancarlo Agnelli; Gary Raskob; Jim Julian; Jack Hirsh; Clive Kearon
Journal:  BMJ       Date:  2011-05-24

Review 6.  Duration of treatment with vitamin K antagonists in symptomatic venous thromboembolism.

Authors:  Saskia Middeldorp; Martin H Prins; Barbara A Hutten
Journal:  Cochrane Database Syst Rev       Date:  2014-08-05
  6 in total

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