Literature DB >> 3581702

Antibodies to extractable cellular antigens in Spanish systemic lupus erythematosus (SLE) patients.

P E Carreira, I Mateo, G Garcia, G Garrido, J Gomez-Reino.   

Abstract

We studied the frequency of antibodies to extractable cellular antigens in 90 Spanish SLE patients. Antibodies to Sm, nRNP, Ro and La were found, respectively, in 6 (6.6%), 18 (20%), 30 (33.3%) and 6 (6.6%) patients. In spite of HLA differences, these results are similar to those found by other authors in Caucasian SLE patients. Our only relevant association was the finding of severe renal disease and high frequency of anti-DNA and hypocomplementemia in patients with antibodies to Ro. Based on these and earlier findings, we discuss the possibility that the immune response to Ro in Spanish patients might be located in a unique extended HLA-complement haplotype.

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Year:  1987        PMID： 3581702     DOI： 10.1007/bf02201006

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN： 0770-3198            Impact factor:   2.980


  15 in total

1.  Profiles of antinuclear antibodies in systemic rheumatic diseases.

Authors:  D D Notman; N Kurata; E M Tan
Journal:  Ann Intern Med       Date:  1975-10       Impact factor: 25.391

2.  Autoantibodies in lupus and its variants: experience in 1000 patients.

Authors:  G R Hughes
Journal:  Br Med J (Clin Res Ed)       Date:  1984-08-11

3.  Purification of an acidic nuclear protein antigen and demonstration of its antibodies in subsets of patients with sicca syndrome.

Authors:  M Akizuki; M J Boehm-Truitt; S S Kassan; A D Steinberg; T M Chused
Journal:  J Immunol       Date:  1977-09       Impact factor: 5.422

4.  The 1982 revised criteria for the classification of systemic lupus erythematosus.

Authors:  E M Tan; A S Cohen; J F Fries; A T Masi; D J McShane; N F Rothfield; J G Schaller; N Talal; R J Winchester
Journal:  Arthritis Rheum       Date:  1982-11

5.  Antibodies to extractable nuclear antigens in 173 patients with DNA-binding positive SLE: an association between antibodies to ribonucleoprotein and Sm antigens observed by counterimmunoelectrophoresis.

Authors:  C C Bunn; A E Gharavi; G R Hughes
Journal:  J Clin Lab Immunol       Date:  1982-05

6.  Serologic and HLA associations in subacute cutaneous lupus erythematosus, a clinical subset of lupus erythematosus.

Authors:  R D Sontheimer; P J Maddison; M Reichlin; R E Jordon; P Stastny; J N Gilliam
Journal:  Ann Intern Med       Date:  1982-11       Impact factor: 25.391

7.  Serologic subsets in systemic lupus erythematosus: an examination of autoantibodies in relationship to clinical features of disease and HLA antigens.

Authors:  D A Bell; P J Maddison
Journal:  Arthritis Rheum       Date:  1980-11

8.  The clinical significance of autoantibodies to a soluble cytoplasmic antigen in systemic lupus erythematosus and other connective tissue diseases.

Authors:  P Maddison; H Mogavero; T T Provost; M Reichlin
Journal:  J Rheumatol       Date:  1979 Mar-Apr       Impact factor: 4.666

9.  Autoantibodies to nonhistone nuclear antigens and their clinical significance.

Authors:  R M Nakamura; E M Tan
Journal:  Hum Pathol       Date:  1983-05       Impact factor: 3.466

10.  Clinical and serological differences between systemic lupus erythematosus patients with antibodies to Ro versus patients with antibodies to Ro and La.

Authors:  C A Wasicek; M Reichlin
Journal:  J Clin Invest       Date:  1982-04       Impact factor: 14.808
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