Literature DB >> 35816151

A scorpion toxin takes the sting out of T cell activation.

Ben Short.   

Abstract

JGP study identifies a novel peptide in scorpion venom that inhibits KV1.2 and KV1.3 channels and could form the basis for new treatments for autoimmune diseases.
© 2022 Rockefeller University Press.

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Year:  2022        PMID： 35816151      PMCID： PMC9276785          DOI： 10.1085/jgp.202213220

Source DB:  PubMed          Journal:  J Gen Physiol        ISSN： 0022-1295            Impact factor:   4.000


  4 in total

Review 1.  Ion channels and transporters in lymphocyte function and immunity.

Authors:  Stefan Feske; Edward Y Skolnik; Murali Prakriya
Journal:  Nat Rev Immunol       Date:  2012-06-15       Impact factor: 53.106

2.  Cm28, a scorpion toxin having a unique primary structure, inhibits KV1.2 and KV1.3 with high affinity.

Authors:  Muhammad Umair Naseem; Edson Carcamo-Noriega; José Beltrán-Vidal; Jesus Borrego; Tibor G Szanto; Fernando Z Zamudio; Gustavo Delgado-Prudencio; Lourival D Possani; Gyorgy Panyi
Journal:  J Gen Physiol       Date:  2022-06-14       Impact factor: 4.000

3.  Kalium 2.0, a comprehensive database of polypeptide ligands of potassium channels.

Authors:  Valentin M Tabakmakher; Nikolay A Krylov; Alexey I Kuzmenkov; Roman G Efremov; Alexander A Vassilevski
Journal:  Sci Data       Date:  2019-05-27       Impact factor: 6.444

4.  Colombian Scorpion Centruroides margaritatus: Purification and Characterization of a Gamma Potassium Toxin with Full-Block Activity on the hERG1 Channel.

Authors:  José Beltrán-Vidal; Edson Carcamo-Noriega; Nina Pastor; Fernando Zamudio-Zuñiga; Jimmy Alexander Guerrero-Vargas; Santiago Castaño; Lourival Domingos Possani; Rita Restano-Cassulini
Journal:  Toxins (Basel)       Date:  2021-06-08       Impact factor: 4.546
  4 in total

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