Literature DB >> 3581431

Toxic and carcinogenic agents in undiluted mainstream smoke and sidestream smoke of different types of cigarettes.

J D Adams, K J O'Mara-Adams, D Hoffmann.   

Abstract

The mainstream and sidestream smoke of four types of popular US cigarettes were analyzed for toxic and carcinogenic agents. The cigarettes included one without a filter tip, and one filter cigarette each with medium, low and ultra-low smoke yields. The analyses clearly demonstrated that 12 toxic agents determined in this study were significantly reduced in the mainstream smoke of filter cigarettes, as compared with smoke yields from the nonfilter cigarette. In the case of the ultra-low yield cigarette, mainstream smoke emissions were reduced by about 90%. In contrast to this finding, the emissions of the same toxic and carcinogenic components into sidestream smoke of the filter cigarettes were not greatly reduced. Sidestream smoke is the major contributor to environmental tobacco smoke, to which both smokers and non-smokers are exposed. Although the exposure of the smoker to mainstream smoke components is decreased due to proportionally greater consumption of low and ultra-low yield cigarettes, and lower rates of consumption of cigarettes with high smoke yields, the carcinogenic potential of indoor pollutants originating from tobacco products is not diminished.

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Year:  1987        PMID: 3581431     DOI: 10.1093/carcin/8.5.729

Source DB:  PubMed          Journal:  Carcinogenesis        ISSN: 0143-3334            Impact factor:   4.944


  23 in total

1.  Nicotelline: a proposed biomarker and environmental tracer for particulate matter derived from tobacco smoke.

Authors:  Peyton Jacob; Maciej L Goniewicz; Christopher M Havel; Suzaynn F Schick; Neal L Benowitz
Journal:  Chem Res Toxicol       Date:  2013-10-14       Impact factor: 3.739

Review 2.  Second-hand smoke and human lung cancer.

Authors:  Ahmad Besaratinia; Gerd P Pfeifer
Journal:  Lancet Oncol       Date:  2008-07       Impact factor: 41.316

3.  Cytokinesis-blocked micronucleus cytome assay biomarkers identify lung cancer cases amongst smokers.

Authors:  Randa A El-Zein; Michael Fenech; Mirtha S Lopez; Margaret R Spitz; Carol J Etzel
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2008-05       Impact factor: 4.254

4.  Cigarette smoke cadmium breakthrough from traditional filters: implications for exposure.

Authors:  R Steven Pappas; Mark R Fresquez; Clifford H Watson
Journal:  J Anal Toxicol       Date:  2014-10-13       Impact factor: 3.367

5.  Protective effect of aerobic exercise on the vocal folds against cigarette smoke exposure.

Authors:  Ceren Ersoz Unlu; Özlem Akkoca; Ilkan Tatar; Mustafa Fevzi Sargon; Dilara Zeybek; Serpil Oguztuzun
Journal:  Eur Arch Otorhinolaryngol       Date:  2019-04-12       Impact factor: 2.503

6.  Tobacco-specific nitrosamines--metabolism and biological monitoring of exposure to tobacco products.

Authors:  E Richter; G Schäffler; A Malone; J Schulze
Journal:  Clin Investig       Date:  1992 Mar-Apr

7.  Volatile N-nitrosamines in mainstream cigarette smoke: occurrence and formation.

Authors:  A R Tricker; R Preussmann
Journal:  Clin Investig       Date:  1992 Mar-Apr

8.  A common carcinogen benzo[a]pyrene causes neuronal death in mouse via microglial activation.

Authors:  Kallol Dutta; Debapriya Ghosh; Arshed Nazmi; Kanhaiya Lal Kumawat; Anirban Basu
Journal:  PLoS One       Date:  2010-04-01       Impact factor: 3.240

9.  Behavioral effects induced by acute exposure to benzo(a)pyrene in F-344 rats.

Authors:  C R Saunders; D C Shockley; M E Knuckles
Journal:  Neurotox Res       Date:  2001-11       Impact factor: 3.911

10.  Biomonitoring of hemoglobin adducts: aromatic amines and tobacco-specific nitrosamines.

Authors:  B Falter; C Kutzer; E Richter
Journal:  Clin Investig       Date:  1994-05
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