Literature DB >> 35813015

Retrospective Analysis of Total Parietal Peritonectomy Without Systematic Lymphadenectomy for Advanced Epithelial Ovarian Cancer.

Suguru Odajima1, Hiroshi Tanabe1, Yuki Koike1, Kota Yokosu1.   

Abstract

BACKGROUND/AIM: Total parietal peritonectomy (TPP) is a surgical procedure used for complete resection of microscopic peritoneal dissemination. This study analyzed the perioperative complications that developed when omitting systematic lymphadenectomy from TPP. PATIENTS AND METHODS: We retrospectively analyzed perioperative complications in epithelial ovarian cancer patients with stage IIIB-IVB who underwent TPP during primary and interval cytoreductive surgeries between April 2018 and October 2021.
RESULTS: Thirty-three patients were enrolled in the study. The median patient age was 62 years. Of 31 patients (94%) with stage IIIC/IV disease, 24 (73%) had high-grade serous carcinoma. The median operative time and blood loss were 447 min and 2,831 ml, respectively. Complete tumor resection was performed in 30 patients (91%). Only five patients underwent partial lymphadenectomy for clinical metastatic lymph nodes. Further, grade 3 complications were observed in seven (21%) patients, and there were no fatal events in this study. Three patients (9%) had ureteric injuries, which was the most frequent complication in this study. Only one patient developed an intra-abdominal infection due to ascites. In this case, partial para-aortic and pelvic lymphadenectomies were performed.
CONCLUSION: TPP without systematic lymphadenectomy reduces the frequency of perioperative complications associated with ascites. Copyright 2022, International Institute of Anticancer Research.

Entities:  

Keywords:  Carcinoma; cytoreduction surgical procedures; intraabdominal infections; lymph node excision; ovarian epithelial

Year:  2022        PMID: 35813015      PMCID: PMC9254101          DOI: 10.21873/cdp.10131

Source DB:  PubMed          Journal:  Cancer Diagn Progn        ISSN: 2732-7787


  31 in total

1.  Bowel resection or repair at the time of cytoreductive surgery for ovarian malignancy is associated with increased complication rate: An ACS-NSQIP study.

Authors:  Laurence Bernard; Julia Boucher; Limor Helpman
Journal:  Gynecol Oncol       Date:  2020-07-06       Impact factor: 5.482

Review 2.  A comparison of outcomes following total and selective peritonectomy performed at the time of interval cytoreductive surgery for advanced serous epithelial ovarian, fallopian tube and primary peritoneal cancer - A study by INDEPSO.

Authors:  Snita Sinukumar; Firoz Rajan; Sanket Mehta; Dileep Damodaran; Shabber Zaveri; Praveen Kammar; Aditi Bhatt
Journal:  Eur J Surg Oncol       Date:  2019-02-23       Impact factor: 4.424

3.  Upper abdominal procedures in advanced stage ovarian or primary peritoneal carcinoma patients with minimal or no gross residual disease: an analysis of Gynecologic Oncology Group (GOG) 182.

Authors:  Noah Rodriguez; Austin Miller; Scott D Richard; Bunja Rungruang; Chad A Hamilton; Michael A Bookman; G Larry Maxwell; Neil S Horowitz; Thomas C Krivak
Journal:  Gynecol Oncol       Date:  2013-06-17       Impact factor: 5.482

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Journal:  CA Cancer J Clin       Date:  2015-01-05       Impact factor: 508.702

5.  Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a meta-analysis.

Authors:  Robert E Bristow; Rafael S Tomacruz; Deborah K Armstrong; Edward L Trimble; F J Montz
Journal:  J Clin Oncol       Date:  2002-03-01       Impact factor: 44.544

6.  Prognostic Value of Peritoneal Cancer Index After Complete Cytoreductive Surgery in Advanced Ovarian Cancer.

Authors:  Mihaela Asp; Susanne Malander; Johan Bengtsson; Hanna Sartor; Paivi Kannisto
Journal:  Anticancer Res       Date:  2022-05       Impact factor: 2.480

7.  Investigation of the freely available easy-to-use software 'EZR' for medical statistics.

Authors:  Y Kanda
Journal:  Bone Marrow Transplant       Date:  2012-12-03       Impact factor: 5.483

8.  Fluid and cellular pathways of rat lymph nodes in relation to lymphatic labyrinths and Aquaporin-1 expression.

Authors:  Osamu Ohtani; Yuko Ohtani; Colin J Carati; Bren J Gannon
Journal:  Arch Histol Cytol       Date:  2003-08

Review 9.  Clinical Impact of Lymphadenectomy after Neoadjuvant Chemotherapy in Advanced Epithelial Ovarian Cancer: A Review of Available Data.

Authors:  Stephanie Seidler; Meriem Koual; Guillaume Achen; Enrica Bentivegna; Laure Fournier; Nicolas Delanoy; Huyên-Thu Nguyen-Xuan; Anne-Sophie Bats; Henri Azaïs
Journal:  J Clin Med       Date:  2021-01-18       Impact factor: 4.241

10.  Total parietal peritonectomy in primary debulking surgery for advanced ovarian cancer.

Authors:  Kota Yokosu; Hiroshi Tanabe; Shogo Nomura; Hirokazu Ozone; Motoaki Saito; Hirokuni Takano; Aikou Okamoto
Journal:  Gynecol Oncol Rep       Date:  2021-06-11
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