Literature DB >> 35812361

Restoring partial vision to a blind patient.

Larry I Benowitz1, John E Dowling2, Roman J Giger3, Thomas V Johnson4, Donald J Zack5.   

Abstract

This paper reports an important breakthrough in partially restoring sight to a man who had lost his vision due to retinitis pigmentosa (RP), a heritable retinal degenerative disease that affects approximately 1 in 4000 people. Long considered an insurmountable challenge, a stellar team of vision scientists, engineers, basic biologists, and others, working together for many years, has enabled a man who had been legally blind for decades to begin distinguishing objects and navigating his environment1. Copyright:
© 2022 Faculty Opinions Ltd.

Entities:  

Keywords:  RGC; Retinitis pigmentosa; cones; retinal ganglion cells; rods

Year:  2022        PMID: 35812361      PMCID: PMC9239363          DOI: 10.12703/r-01-0000012

Source DB:  PubMed          Journal:  Fac Rev        ISSN: 2732-432X


  8 in total

Review 1.  Retinitis pigmentosa.

Authors:  Dyonne T Hartong; Eliot L Berson; Thaddeus P Dryja
Journal:  Lancet       Date:  2006-11-18       Impact factor: 79.321

Review 2.  Gene therapy and genome surgery in the retina.

Authors:  James E DiCarlo; Vinit B Mahajan; Stephen H Tsang
Journal:  J Clin Invest       Date:  2018-06-01       Impact factor: 14.808

Review 3.  The types of retinal ganglion cells: current status and implications for neuronal classification.

Authors:  Joshua R Sanes; Richard H Masland
Journal:  Annu Rev Neurosci       Date:  2015-04-09       Impact factor: 12.449

4.  Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina.

Authors:  Yi-Rong Peng; Karthik Shekhar; Wenjun Yan; Dustin Herrmann; Anna Sappington; Gregory S Bryman; Tavé van Zyl; Michael Tri H Do; Aviv Regev; Joshua R Sanes
Journal:  Cell       Date:  2019-01-31       Impact factor: 41.582

5.  Development of pattern vision following early and extended blindness.

Authors:  Amy Kalia; Luis Andres Lesmes; Michael Dorr; Tapan Gandhi; Garga Chatterjee; Suma Ganesh; Peter J Bex; Pawan Sinha
Journal:  Proc Natl Acad Sci U S A       Date:  2014-01-21       Impact factor: 11.205

6.  Results of late surgical intervention in children with early-onset bilateral cataracts.

Authors:  Suma Ganesh; Priyanka Arora; Sumita Sethi; Tapan K Gandhi; Amy Kalia; Garga Chatterjee; Pawan Sinha
Journal:  Br J Ophthalmol       Date:  2014-05-30       Impact factor: 4.638

7.  Partial recovery of visual function in a blind patient after optogenetic therapy.

Authors:  José-Alain Sahel; Elise Boulanger-Scemama; Chloé Pagot; Angelo Arleo; Francesco Galluppi; Joseph N Martel; Simona Degli Esposti; Alexandre Delaux; Jean-Baptiste de Saint Aubert; Caroline de Montleau; Emmanuel Gutman; Isabelle Audo; Jens Duebel; Serge Picaud; Deniz Dalkara; Laure Blouin; Magali Taiel; Botond Roska
Journal:  Nat Med       Date:  2021-05-24       Impact factor: 87.241

8.  Optogenetic therapy: high spatiotemporal resolution and pattern discrimination compatible with vision restoration in non-human primates.

Authors:  Gregory Gauvain; Himanshu Akolkar; Antoine Chaffiol; Fabrice Arcizet; Mina A Khoei; Mélissa Desrosiers; Céline Jaillard; Romain Caplette; Olivier Marre; Stéphane Bertin; Claire-Maelle Fovet; Joanna Demilly; Valérie Forster; Elena Brazhnikova; Philippe Hantraye; Pierre Pouget; Anne Douar; Didier Pruneau; Joël Chavas; José-Alain Sahel; Deniz Dalkara; Jens Duebel; Ryad Benosman; Serge Picaud
Journal:  Commun Biol       Date:  2021-01-27
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.