| Literature DB >> 35812034 |
Lucia Macken1, Margaret Corrigan2, Wendy Prentice3, Fiona Finlay4, Joanne McDonagh5, Neil Rajoriya5, Claire Salmon6, Mhairi Donnelly7, Catherine Evans8, Bhaskar Ganai1, Joan Bedlington9, Shani Steer10, Mark Wright11, Ben Hudson12, Sumita Verma1,13.
Abstract
Palliative care remains suboptimal in advanced cirrhosis, in part relating to a lack of evidence-based interventions. Ascites remains the most common cirrhosis complication resulting in hospitalisation. Many patients with refractory ascites are not candidates for liver transplantation or transjugular intrahepatic portosystemic shunt, and therefore, require recurrent palliative large volume paracentesis in hospital. We review the available evidence on use of palliative long-term abdominal drains in cirrhosis. Pending results of a national trial (REDUCe 2) and consistent with recently published national and American guidance, long-term abdominal drains cannot be regarded as standard of care in advanced cirrhosis. They should instead be considered only on a case-by-case basis, pending definitive evidence. This manuscript provides consensus to help standardise use of long-term abdominal drains in cirrhosis including patient selection and community management. Our ultimate aim remains to improve palliative care for this under researched and vulnerable cohort. © Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.Entities:
Keywords: ASCITES; CLINICAL TRIALS; LIVER CIRRHOSIS; PERITONITIS
Year: 2022 PMID: 35812034 PMCID: PMC9234735 DOI: 10.1136/flgastro-2022-102128
Source DB: PubMed Journal: Frontline Gastroenterol ISSN: 2041-4137