Literature DB >> 35810246

Neonatal abstinence syndrome: Effectiveness of targeted umbilical cord drug screening.

Alecia J Karr1,2,3, Mary Kay Rayens4, Leslie K Scott4.   

Abstract

OBJECTIVE: This study sought to determine if targeted drug screening of newborns was effective in identifying a positive drug test result. STUDY
DESIGN: This was a retrospective cross-sectional study. A total of 340 infants met criteria for drug screening. Sensitivity and specificity were used to evaluate each of the potential risk factors in terms of their ability to predict a positive drug test result. Two-sample t-tests were used to compare differences in Finnegan scores between babies with a positive drug test result and those with a negative one. RESULT: The risk factor with the highest sensitivity was maternal history of drug use. The difference in the Finnegan scores between groups was statistically significant.
CONCLUSION: The risk factors associated with this study were not very sensitive. The only way to identify all infants at risk of NAS is to standardize the screening process and apply to all infants.
© 2022. The Author(s), under exclusive licence to Springer Nature America, Inc.

Entities:  

Mesh:

Year:  2022        PMID: 35810246     DOI: 10.1038/s41372-022-01457-8

Source DB:  PubMed          Journal:  J Perinatol        ISSN: 0743-8346            Impact factor:   3.225


  14 in total

1.  Infant race affects application of clinical guidelines when screening for drugs of abuse in newborns.

Authors:  Marc A Ellsworth; Timothy P Stevens; Carl T D'Angio
Journal:  Pediatrics       Date:  2010-05-17       Impact factor: 7.124

Review 2.  Long-Term Outcomes of Infants with Neonatal Abstinence Syndrome.

Authors:  Denise J Maguire; Susan Taylor; Kathleen Armstrong; Emily Shaffer-Hudkins; Aaron M Germain; Sandra S Brooks; Genieveve J Cline; Leah Clark
Journal:  Neonatal Netw       Date:  2016

3.  Identifying infants at risk for neonatal abstinence syndrome: a retrospective cohort comparison study of 3 screening approaches.

Authors:  Jodie Murphy-Oikonen; William J Montelpare; Sarah Southon; Larry Bertoldo; Nancy Persichino
Journal:  J Perinat Neonatal Nurs       Date:  2010 Oct-Dec       Impact factor: 1.638

4.  The prevalence of prenatal opioid and other drug use in Utah.

Authors:  Karen F Buchi; Carla Suarez; Michael W Varner
Journal:  Am J Perinatol       Date:  2012-08-09       Impact factor: 1.862

Review 5.  Neonatal Abstinence Syndrome.

Authors:  Karen McQueen; Jodie Murphy-Oikonen
Journal:  N Engl J Med       Date:  2016-12-22       Impact factor: 91.245

6.  Comparison of umbilical cord tissue and meconium for the confirmation of in utero drug exposure.

Authors:  Jennifer M Colby
Journal:  Clin Biochem       Date:  2017-03-11       Impact factor: 3.281

7.  Neonatal Abstinence Syndrome and Ethical Approaches to the Identification of Pregnant Women Who Use Drugs.

Authors:  Mishka Terplan; Howard Minkoff
Journal:  Obstet Gynecol       Date:  2017-01       Impact factor: 7.661

8.  Screening, testing, and reporting for drug and alcohol use on labor and delivery: a survey of Maryland birthing hospitals.

Authors:  Catherine Miller; Amy Lanham; Christopher Welsh; Shaalini Ramanadhan; Mishka Terplan
Journal:  Soc Work Health Care       Date:  2014

9.  Wide Variation Found in Care of Opioid-Exposed Newborns.

Authors:  Debra L Bogen; Bonny L Whalen; Laura R Kair; Mark Vining; Beth A King
Journal:  Acad Pediatr       Date:  2016-11-23       Impact factor: 3.107

10.  A Quality Improvement Initiative to Increase Scoring Consistency and Accuracy of the Finnegan Tool: Challenges in Obtaining Reliable Assessments of Drug Withdrawal in Neonatal Abstinence Syndrome.

Authors:  Wendy Timpson; Cheryl Killoran; Louise Maranda; Alan Picarillo; Elisabeth Bloch-Salisbury
Journal:  Adv Neonatal Care       Date:  2018-02       Impact factor: 1.968

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