Jingjing Ming1,2, Lingzhi Chen3, Tianyi Chen4, James R Hébert5,6,7, Peng Sun8, Li Zhang9, Hongya Wang10, Qingkuo Wu11, Cancan Zhang8, Nitin Shivappa5,6,7, Bo Ban12,13. 1. Department of Emergency Trauma Surgery, Jining No. 1 People's Hospital, Jining, 272029, Shandong, China. 2. School of Nursing, Shandong First Medical University, Shandong Academy of Medical Sciences, Tai'an, 271000, Shandong, China. 3. Department of Clinical Nutrition, Affiliated Hospital of Jining Medical University, Jining, 272029, Shandong, China. 15264797966@163.com. 4. Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, 150081, Heilongjiang, China. 5. Cancer Prevention and Control Program, University of South Carolina, 915 Greene Street, Suite 200, Columbia, SC, 29208, USA. 6. Department of Epidemiology and Biostatistics, University of South Carolina, 915 Greene Street, Suite 400, Columbia, SC, 29208, USA. 7. Department of Nutrition, Connecting Health Innovations, LLC, 1417 Gregg Street, Columbia, SC, 29201, USA. 8. Department of Clinical Nutrition, Affiliated Hospital of Jining Medical University, Jining, 272029, Shandong, China. 9. Department of Clinical Nutrition, Yan Tai Yu Huang Ding Hospital, Yantai, 264000, Shandong, China. 10. Department of Obstetrics, Affiliated Hospital of Jining Medical University, Jining, 272029, Shandong, China. 11. Department of Clinical Nutrition, Tumor Hospital of Jining, Jining, 272029, Shandong, China. 12. Department of Endocrinology, Affiliated Hospital of Jining Medical University, Jining, 272029, Shandong, China. banbo2011@163.com. 13. Chinese Research Center for Behavior Medicine in Growth and Development, Jining, 272029, Shandong, China. banbo2011@163.com.
Abstract
PURPOSE: Chronic low-grade systemic inflammation affects muscle protein metabolism. The dietary inflammatory index (DII®) is a tool designed to assess the inflammatory potential of the diet. The available data on the association between DII and sarcopenia are limited. We aimed to investigate the association of the DII with components of sarcopenia in individuals over 50 years of age. METHODS: This cross-sectional study used the National Health and Nutrition Examination Survey (NHANES) 1999-2002 dataset. Body composition was measured, and isokinetic strength of the knee extensors (peak force) was evaluated. Low muscle mass and strength were defined using sex-specific thresholds. Energy-adjusted DII (E-DII™) scores were calculated using 24-h dietary recall data. Regression models were fit to evaluate the association between E-DII scores and low muscle mass and low muscle strength, alone and combined. RESULTS: Mean age of study participants was 62.1 ± 9.5 years, and 138 participants (7.4%) belonged to the combination group of low muscle mass and low muscle strength. In multivariable-adjusted regression models, higher E-DII score was associated with lower appendicular skeletal muscle index (ASMI) (β = - 0.03, P < 0.001, P trend <0.001), and lower peak force (β = -2.15, P = 0.04, P trend = 0.01) and higher likelihood for these components combined (OR = 1.12, 95% CI 1.01-1.25, P = 0.03). CONCLUSION: Higher E-DII score is associated with lower muscle mass and muscle strength, and increased likelihood for the combination of low muscle mass and low muscle strength in older adults. This has important implications for healthy aging.
PURPOSE: Chronic low-grade systemic inflammation affects muscle protein metabolism. The dietary inflammatory index (DII®) is a tool designed to assess the inflammatory potential of the diet. The available data on the association between DII and sarcopenia are limited. We aimed to investigate the association of the DII with components of sarcopenia in individuals over 50 years of age. METHODS: This cross-sectional study used the National Health and Nutrition Examination Survey (NHANES) 1999-2002 dataset. Body composition was measured, and isokinetic strength of the knee extensors (peak force) was evaluated. Low muscle mass and strength were defined using sex-specific thresholds. Energy-adjusted DII (E-DII™) scores were calculated using 24-h dietary recall data. Regression models were fit to evaluate the association between E-DII scores and low muscle mass and low muscle strength, alone and combined. RESULTS: Mean age of study participants was 62.1 ± 9.5 years, and 138 participants (7.4%) belonged to the combination group of low muscle mass and low muscle strength. In multivariable-adjusted regression models, higher E-DII score was associated with lower appendicular skeletal muscle index (ASMI) (β = - 0.03, P < 0.001, P trend <0.001), and lower peak force (β = -2.15, P = 0.04, P trend = 0.01) and higher likelihood for these components combined (OR = 1.12, 95% CI 1.01-1.25, P = 0.03). CONCLUSION: Higher E-DII score is associated with lower muscle mass and muscle strength, and increased likelihood for the combination of low muscle mass and low muscle strength in older adults. This has important implications for healthy aging.
Authors: Bertrand Léger; Romain Cartoni; Manu Praz; Séverine Lamon; Olivier Dériaz; Antoinette Crettenand; Charles Gobelet; Paul Rohmer; Michel Konzelmann; François Luthi; Aaron P Russell Journal: J Physiol Date: 2006-08-17 Impact factor: 5.182
Authors: Scott K Powers; Rafael Deminice; Mustafa Ozdemir; Toshinori Yoshihara; Matthew P Bomkamp; Hayden Hyatt Journal: J Sport Health Sci Date: 2020-05-04 Impact factor: 7.179