Literature DB >> 3580516

Definition of mean residence times in pharmacokinetics.

D J Cutler.   

Abstract

A new definition of the mean residence time is proposed which includes the commonly used definition as a special case. The advantage of the new definition is that it applies for both linear and non-linear systems. Some practical advantages which follow from the new definition are discussed. Procedures for using urinary excretion data in mean residence time estimation are discussed.

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Year:  1987        PMID： 3580516     DOI： 10.1002/bdd.2510080110

Source DB:  PubMed          Journal:  Biopharm Drug Dispos        ISSN： 0142-2782            Impact factor:   1.627


  10 in total

1.  The relevance of residence time theory to pharmacokinetics.

Authors:  M Weiss
Journal:  Eur J Clin Pharmacol       Date:  1992       Impact factor: 2.953

Review 2.  Mean time parameters in pharmacokinetics. Definition, computation and clinical implications (Part II).

Authors:  P Veng-Pedersen
Journal:  Clin Pharmacokinet       Date:  1989-12       Impact factor: 6.447

Review 3.  The phenomenon and rationale of marked dependence of drug concentration on blood sampling site. Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (Part II).

Authors:  W L Chiou
Journal:  Clin Pharmacokinet       Date:  1989-10       Impact factor: 6.447

4.  Mean residence times and distribution volumes for drugs undergoing linear reversible metabolism and tissue distribution and linear or nonlinear elimination from the central compartments.

Authors:  H Y Cheng; W J Jusko
Journal:  Pharm Res       Date:  1991-04       Impact factor: 4.200

5.  Application of mean residence-time concepts to pharmacokinetic systems with noninstantaneous input and nonlinear elimination.

Authors:  H Y Cheng; W J Jusko
Journal:  Pharm Res       Date:  1989-01       Impact factor: 4.200

6.  Calculations and application of mean residence times for drugs which demonstrate one-compartment distribution and Michaelis-Menten elimination.

Authors:  J A Cook; P R Gwilt
Journal:  Pharm Res       Date:  1988-03       Impact factor: 4.200

7.  Mean residence time concepts for pharmacokinetic systems with nonlinear drug elimination described by the Michaelis-Menten equation.

Authors:  H Y Cheng; W J Jusko
Journal:  Pharm Res       Date:  1988-03       Impact factor: 4.200

8.  General treatment of mean residence time, clearance, and volume parameters in linear mammillary models with elimination from any compartment.

Authors:  E Nakashima; L Z Benet
Journal:  J Pharmacokinet Biopharm       Date:  1988-10

9.  The non-compartmental steady-state volume of distribution revisited.

Authors:  Wojciech Jawień; Jan Kobierski
Journal:  J Pharmacokinet Pharmacodyn       Date:  2020-01-03       Impact factor: 2.745

10.  Methylprednisolone pharmacokinetics after intravenous and oral administration.

Authors:  S M Al-Habet; H J Rogers
Journal:  Br J Clin Pharmacol       Date:  1989-03       Impact factor: 4.335
  10 in total

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