Literature DB >> 3580470

Surface characteristics and the interaction of colloidal particles with mouse peritoneal macrophages.

L Illum, L O Jacobsen, R H Müller, E Mak, S S Davis.   

Abstract

The effect of surface characteristics on the interaction of sterically stabilized polystyrene particles with mouse peritoneal macrophages was studied using a range of poloxamers and poloxamine as coating agents. The coated particles were characterized in terms of thickness of coating layer, surface charge and critical flocculation temperature. The relative phagocytic uptake was found to decrease with increasing adsorbed layer thickness i.e. longer hydrophilic polymer chains of the coating agent and consequently a greater steric stabilization effect.

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Year:  1987        PMID： 3580470     DOI： 10.1016/0142-9612(87)90099-8

Source DB:  PubMed          Journal:  Biomaterials        ISSN： 0142-9612            Impact factor:   12.479


  17 in total

Review 1.  Methods for the preparation and manufacture of polymeric nanoparticles.

Authors:  Christine Vauthier; Kawthar Bouchemal
Journal:  Pharm Res       Date:  2008-12-24       Impact factor: 4.200

2.  Size-dependent biodistribution of thiol-organosilica nanoparticles and F4/80 protein expression in the genital tract of female mice after intravaginal administration.

Authors:  Aziz Awaad; Michihiro Nakamura
Journal:  Histochem Cell Biol       Date:  2021-03-03       Impact factor: 4.304

3.  Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) improves antitumor activity and reduces animal toxicity and immunogenicity.

Authors:  Y Tsutsumi; M Onda; S Nagata; B Lee; R J Kreitman; I Pastan
Journal:  Proc Natl Acad Sci U S A       Date:  2000-07-18       Impact factor: 11.205

4.  Cellular charge of Cryptococcus neoformans: contributions from the capsular polysaccharide, melanin, and monoclonal antibody binding.

Authors:  J D Nosanchuk; A Casadevall
Journal:  Infect Immun       Date:  1997-05       Impact factor: 3.441

5.  Prolonged blood circulation in rats of nanospheres surface-modified with semitelechelic poly[N-(2-hydroxypropyl)methacrylamide].

Authors:  S Kamei; J Kopecek
Journal:  Pharm Res       Date:  1995-05       Impact factor: 4.200

6.  Surface modification of poly(lactide-co-glycolide) nanospheres by biodegradable poly(lactide)-poly(ethylene glycol) copolymers.

Authors:  S Stolnik; S E Dunn; M C Garnett; M C Davies; A G Coombes; D C Taylor; M P Irving; S C Purkiss; T F Tadros; S S Davis
Journal:  Pharm Res       Date:  1994-12       Impact factor: 4.200

7.  Direct suppression of phagocytosis by amphipathic polymeric surfactants.

Authors:  N Watrous-Peltier; J Uhl; V Steel; L Brophy; E Merisko-Liversidge
Journal:  Pharm Res       Date:  1992-09       Impact factor: 4.200

8.  Polystyrene-poly (ethylene glycol) (PS-PEG2000) particles as model systems for site specific drug delivery. 2. The effect of PEG surface density on the in vitro cell interaction and in vivo biodistribution.

Authors:  S E Dunn; A Brindley; S S Davis; M C Davies; L Illum
Journal:  Pharm Res       Date:  1994-07       Impact factor: 4.200

9.  Amphotericin B and fluconazole affect cellular charge, macrophage phagocytosis, and cellular morphology of Cryptococcus neoformans at subinhibitory concentrations.

Authors:  J D Nosanchuk; W Cleare; S P Franzot; A Casadevall
Journal:  Antimicrob Agents Chemother       Date:  1999-02       Impact factor: 5.191

10.  Ligand-specific targeting of microspheres to phagocytes by surface modification with poly(L-lysine)-grafted poly(ethylene glycol) conjugate.

Authors:  Sofia Faraasen; János Vörös; Gábor Csúcs; Marcus Textor; Hans P Merkle; Elke Walter
Journal:  Pharm Res       Date:  2003-02       Impact factor: 4.200
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