Literature DB >> 3580442

Polyol accumulation in human placenta and umbilical cord.

N Toh, T Inoue, H Tanaka, E Kimoto.   

Abstract

Ultrafiltrable metabolites in human term placenta and umbilical cord were analysed by means of 13C-NMR spectroscopy and gas-liquid chromatography. In these tissues, existing in a very reduced redox state, lactate and polyols (sorbitol, myoinositol and xylitol) were found to be the major accumulated intermediates of the glycolytic pathways. The cord tissue preferentially took up myoinositol.

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Year:  1987        PMID： 3580442

Source DB:  PubMed          Journal:  Biol Res Pregnancy Perinatol        ISSN： 0724-438X


  2 in total

1.  Placental Inositol Reduced in Gestational Diabetes as Glucose Alters Inositol Transporters and IMPA1 Enzyme Expression.

Authors:  Reshma A Pillai; Mohammed O Islam; Preben Selvam; Neha Sharma; Anne H Y Chu; Oliver C Watkins; Keith M Godfrey; Rohan M Lewis; Shiao Y Chan
Journal:  J Clin Endocrinol Metab       Date:  2021-01-23       Impact factor: 5.958

2.  High placental inositol content associated with suppressed pro-adipogenic effects of maternal glycaemia in offspring: the GUSTO cohort.

Authors:  Anne H Y Chu; Mya T Tint; Hsin F Chang; Gerard Wong; Wen Lun Yuan; Dedreia Tull; Brunda Nijagal; Vinod K Narayana; Peter J Meikle; Kenneth T E Chang; Rohan M Lewis; Claudia Chi; Fabian K P Yap; Kok Hian Tan; Lynette P Shek; Yap-Seng Chong; Peter D Gluckman; Yung Seng Lee; Marielle V Fortier; Keith M Godfrey; Johan G Eriksson; Neerja Karnani; Shiao-Yng Chan
Journal:  Int J Obes (Lond)       Date:  2020-05-20       Impact factor: 5.095
  2 in total

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