Literature DB >> 3580374

Genetic identification of rat liver carboxylesterases isolated in different laboratories.

R Mentlein, A Ronai, M Robbi, E Heymann, O von Deimling.   

Abstract

Six carboxylesterases previously isolated from rat liver microsomes, characterized in Brussels and in Kiel, were compared with genetically defined liver esterases of various reference strains using polyacrylamide gel electrophoresis and isoelectric focusing. The six liver carboxylesterases were identified as alloenzymic forms of ES-3, ES-4, ES-8/ES-10 and ES-15 according to the genetic nomenclature recommended by van Zutphen (Van Zutphen, L.F.M. (1983) Transplant. Proceed. 15, 1687-1688). The genetic and biochemical characteristics of the four isoenzymes are summarized, and their identity with several other drug-metabolizing esterases/amidases and lipases of rat liver endoplasmic reticulum is discussed.

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Year:  1987        PMID: 3580374     DOI: 10.1016/0167-4838(87)90228-7

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  12 in total

1.  Rat carboxylesterase ES-4 enzyme functions as a major hepatic neutral cholesteryl ester hydrolase.

Authors:  Saj Parathath; Snjezana Dogan; Victor A Joaquin; Snigdha Ghosh; Liang Guo; Ginny L Weibel; George H Rothblat; Earl H Harrison; Edward A Fisher
Journal:  J Biol Chem       Date:  2011-09-20       Impact factor: 5.157

2.  Purification and characterization of carboxylesterases from rat lung.

Authors:  R Gaustad; K Sletten; D Løvhaug; F Fonnum
Journal:  Biochem J       Date:  1991-03-15       Impact factor: 3.857

3.  Nucleotide sequence of cDNA coding for rat liver pI 6.1 esterase (ES-10), a carboxylesterase located in the lumen of the endoplasmic reticulum.

Authors:  M Robbi; H Beaufay; J N Octave
Journal:  Biochem J       Date:  1990-07-15       Impact factor: 3.857

4.  Immunochemical characterization and biosynthesis of pI-6.4 esterase, a carboxylesterase of rat liver microsomal extracts.

Authors:  M Robbi; H Beaufay
Journal:  Biochem J       Date:  1988-08-15       Impact factor: 3.857

5.  Biosynthesis of rat liver pI-6.1 esterase, a carboxylesterase of the cisternal space of the endoplasmic reticulum.

Authors:  M Robbi; H Beaufay
Journal:  Biochem J       Date:  1987-12-01       Impact factor: 3.857

6.  Purification, characterization and modulation of a microsomal carboxylesterase in rat liver for the hydrolysis of acyl-CoA.

Authors:  J J Mukherjee; F T Jay; P C Choy
Journal:  Biochem J       Date:  1993-10-01       Impact factor: 3.857

7.  Esterase-16 (ES-16) of the rat (Rattus norvegicus): identification and genetic characterization.

Authors:  O H von Deimling; B Simon; R Kluge; H Hedrich
Journal:  Biochem Genet       Date:  1988-10       Impact factor: 1.890

8.  Sialic acid 9-O-acetylesterase catalyzes the hydrolyzing reaction from alacepril to deacetylalacepril.

Authors:  Shigeyuki Usui; Masafumi Kubota; Kazuhiro Iguchi; Tadashi Kiho; Tadashi Sugiyama; Yoshihiro Katagiri; Kazuyuki Hirano
Journal:  Pharm Res       Date:  2003-08       Impact factor: 4.200

9.  Specificity of the sex-influenced esterase (ES-SI) isozyme in rat liver.

Authors:  H Nikaido; T Hirose; O Nikaido; J Yamada; J Hayakawa
Journal:  Biochem Genet       Date:  1991-06       Impact factor: 1.890

10.  Cloning and sequencing of rat liver carboxylesterase ES-4 (microsomal palmitoyl-CoA hydrolase).

Authors:  M Robbi; E Van Schaftingen; H Beaufay
Journal:  Biochem J       Date:  1996-02-01       Impact factor: 3.857

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