Dauda Eneyamire Suleiman1, Almustapha Aliyu Liman2, Garba Dahiru Waziri2, Yawale Iliyasu3, Saad Aliyu Ahmed2. 1. Department of Histopathology, College of Medical Sciences, Abubakar Tafawa Balewa University, Bauchi, 7204212, Nigeria. desuleiman@atbu.edu.ng. 2. Departent of Pathology, College of Medical Sciences, Ahmadu Bello University, Zaria, Nigeria. 3. Department of Anatomic Pathology and Forensic Medicine, Faculty of Clinical Sciences, Kaduna State University, Kaduna, Nigeria.
Abstract
BACKGROUND: Ocular surface squamous neoplasia (OSSN) is a heterogeneous group of proliferative squamous lesions on the ocular surface with varying biologic behaviours. This study aims to report the clinical profile and pathological characteristics of cases of OSSN seen at a tertiary referral centre in North West Nigeria. METHODS: A retrospective review of all cases of OSSN diagnosed over a 10-year period was done. RESULTS: OSSN accounted for 68 out of 91 ocular surface lesions affecting twice as many males as females and a peak incidence in the 30-39 years age group. They frequently presented as higher-grade and higher-stage lesions with invasive squamous cell carcinoma being the most frequently diagnosed OSSN. They also frequently showed an association with HIV infection and a relatively long duration of symptoms before presentation. CONCLUSION: OSSN occurs in a relatively young age group in our environment. Certain clinical and epidemiological features appear to predict the occurrence of higher-grade lesions, and this may help in the clinical prediction of likely pathologic grade and/or biologic behaviour of these lesions.
BACKGROUND: Ocular surface squamous neoplasia (OSSN) is a heterogeneous group of proliferative squamous lesions on the ocular surface with varying biologic behaviours. This study aims to report the clinical profile and pathological characteristics of cases of OSSN seen at a tertiary referral centre in North West Nigeria. METHODS: A retrospective review of all cases of OSSN diagnosed over a 10-year period was done. RESULTS: OSSN accounted for 68 out of 91 ocular surface lesions affecting twice as many males as females and a peak incidence in the 30-39 years age group. They frequently presented as higher-grade and higher-stage lesions with invasive squamous cell carcinoma being the most frequently diagnosed OSSN. They also frequently showed an association with HIV infection and a relatively long duration of symptoms before presentation. CONCLUSION: OSSN occurs in a relatively young age group in our environment. Certain clinical and epidemiological features appear to predict the occurrence of higher-grade lesions, and this may help in the clinical prediction of likely pathologic grade and/or biologic behaviour of these lesions.
Authors: Andrew A Kao; Anat Galor; Carol L Karp; Amany Abdelaziz; William J Feuer; Sander R Dubovy Journal: Ophthalmology Date: 2012-07-06 Impact factor: 12.079
Authors: Marie B Nguena; Jan G van den Tweel; William Makupa; Victor H Hu; Helen A Weiss; Stephen Gichuhi; Matthew J Burton Journal: Ophthalmology Date: 2013-12-08 Impact factor: 12.079