Literature DB >> 35802155

Pediatric patient with a bilateral Salter-Harris II fracture and slipped capital femoral epiphysis secondary to autosomal recessive osteopetrosis.

Ayham Jaber1, Martin Schwarze2, Verena Steinle3, Marco Götze2, Sébastien Hagmann2.   

Abstract

Treatment of femoral neck fractures secondary to osteopetrosis is an uncertain and puzzled decision. Experience in the treatment, especially in the pediatric population, is scarcely reported. The duration of conservative treatment is prolonged and poses the risks of non-union and development of coxa vara deformity. The recommended treatment is closed reduction and internal fixation; however, surgery on osteopetrotic bone is challenging due to defective bone marrow function, delayed consolidation and higher risk of intraoperative fractures. Slipped capital femoral epiphysis secondary to osteopetrosis is very rarely reported. This article presents the case of a 5-year-old female patient with rapidly deteriorating physical function due to bilateral proximal femoral Salter-Harris type II fractures with associated slippage of the growth plates secondary to confirmed autosomal recessive osteopetrosis. Operative treatment was performed in a tertiary level orthopedic center with closed reduction and internal fixation with cannulated screws. A loss of fixation with coxa vara deformity was seen on the left side 7 months postoperatively with increasing pain. A revision surgery with reosteosynthesis and a valgus osteotomy was thus performed which showed good subjective and objective results 1 year postoperatively with complete bony union.
© 2022. The Author(s).

Entities:  

Keywords:  Congenital disease; Femoral neck fracture; Growth plate; Osteosynthesis; Osteotomy; Pathologic fracture

Year:  2022        PMID: 35802155     DOI: 10.1007/s00132-022-04278-x

Source DB:  PubMed          Journal:  Orthopadie (Heidelb)        ISSN: 2731-7145


  27 in total

1.  The oldest case of osteopetrosis in a human skeleton: exploring the history of rare diseases.

Authors:  Julia Gresky; Roman Sokiranski; Florian Witzmann; Emmanuele Petiti
Journal:  Lancet Diabetes Endocrinol       Date:  2020-10       Impact factor: 32.069

Review 2.  Diagnosis and Management of Osteopetrosis: Consensus Guidelines From the Osteopetrosis Working Group.

Authors:  Calvin C Wu; Michael J Econs; Linda A DiMeglio; Karl L Insogna; Michael A Levine; Paul J Orchard; Weston P Miller; Anna Petryk; Eric T Rush; Dolores M Shoback; Leanne M Ward; Lynda E Polgreen
Journal:  J Clin Endocrinol Metab       Date:  2017-09-01       Impact factor: 5.958

Review 3.  Neurological aspects of osteopetrosis.

Authors:  C G Steward
Journal:  Neuropathol Appl Neurobiol       Date:  2003-04       Impact factor: 8.090

Review 4.  [Osteopetrosis. Classification, etiology, treatment options and implications for oral health].

Authors:  P de Baat; M P Heijboer; C de Baat
Journal:  Ned Tijdschr Tandheelkd       Date:  2005-12

Review 5.  Osteopetrosis.

Authors:  Zornitza Stark; Ravi Savarirayan
Journal:  Orphanet J Rare Dis       Date:  2009-02-20       Impact factor: 4.123

6.  Severe neuronopathic autosomal recessive osteopetrosis due to homozygous deletions affecting OSTM1.

Authors:  Claus-Eric Ott; Björn Fischer; Phillipe Schröter; Reyk Richter; Neerja Gupta; Nishant Verma; Madhulika Kabra; Stefan Mundlos; Anna Rajab; Heidemarie Neitzel; Uwe Kornak
Journal:  Bone       Date:  2013-04-17       Impact factor: 4.398

7.  Infantile osteopetrosis: a case report on dental findings.

Authors:  D Droz-Desprez; C Azou; P Bordigoni; M Bonnaure-Mallet
Journal:  J Oral Pathol Med       Date:  1992-10       Impact factor: 4.253

8.  Clinical and Radiological Findings of Autosomal Dominant Osteopetrosis Type II: A Case Report.

Authors:  Priyanka Kant; Neelkamal Sharda; Rahul R Bhowate
Journal:  Case Rep Dent       Date:  2013-10-24

9.  Extra-skeletal manifestations in mice affected by Clcn7-dependent autosomal dominant osteopetrosis type 2 clinical and therapeutic implications.

Authors:  Mattia Capulli; Antonio Maurizi; Annabel Curle; Rajvi Patel; Argia Ucci; Juliana Alves Côrtes; Harriet Oxford; Shireen R Lamandé; John F Bateman; Nadia Rucci; Anna Teti
Journal:  Bone Res       Date:  2019-06-11       Impact factor: 13.567

10.  A case report of malignant infantile osteopetrosis.

Authors:  Merve Usta; Seda Geylani Gulec; Serap Karaman; Ela Erdem; Hicran Emral; Nafiye Urgancı
Journal:  Iran J Pediatr       Date:  2012-09       Impact factor: 0.364

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