Literature DB >> 35799137

Correction to: Monocyte anisocytosis increases during multisystem inflammatory syndrome in children with cardiovascular complications.

Lael M Yonker1,2,3, Oluwakemi Badaki-Makun4,5, Puneeta Arya6,7, Brittany P Boribong6,8,7, Gabriela Moraru9,10, Brittany Fenner11, Jaimar Rincon11, Alex Hopke7,12,13, Brent Rogers9,10, Jeremiah Hinson4,5,14, Alessio Fasano6,8,7, Lilly Lee9, Sarah M Kehoe15, Shawn D Larson11, Hector Chavez9,10, Scott Levin4,5,14, Lyle L Moldawer11, Daniel Irimia16,17,18.   

Abstract

Entities:  

Year:  2022        PMID: 35799137      PMCID: PMC9260969          DOI: 10.1186/s12879-022-07563-4

Source DB:  PubMed          Journal:  BMC Infect Dis        ISSN: 1471-2334            Impact factor:   3.667


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Correction to: BMC Infectious Diseases (2022) 22:563 https://doi.org/10.1186/s12879-022-07526-9

Following the publication of the original article [1], the authors identified that some symbols were absent in the on-line version of Figs. 4 and 5. These Figures have been corrected.
Fig. 4

MDW depends on MIS-C severity and changes through the course of MIS-C diagnosis, treatment, and recovery. A Higher MDW values in MIS-C patients who manifested cardiac complications (Cardiac MIS-C) compared to children with MIS-C without cardiac involvement or presenting with symptoms concerning MIS-C (fever plus recent/current positive SARS-CoV2 PCR or SARS-CoV2 antibodies positive). B ROC in the validation cohort to assess the utility of MDW as a screening tool for cardiac involvement of MIS-C. AUC = area under the curve (fraction). C Blood from children with MIS-C was collected at multiple time points. MDW was plotted by time of collection: at admission, during hospital course, and at discharge or follow-up. Analysis by one way ANOVA. **P < 0.01, ****P < 0.0001. D MDW values from individual patients with MIS-C are plotted over the course of their illness. Black lines connect individual patients with MIS-C. Not all patients provided blood samples at each time point

Fig. 5

Assessment of other hematological parameters in MIS-C. Hematologic parameters, including A white blood cell (WBC), B neutrophil (PMN), C lymphocyte, D monocyte, and E platelet counts were compared between healthy controls, children with non-infectious illness, children with an infectious/inflammatory illness, and children with MIS-C in the validation cohort. Analysis by ordinary one-way ANOVA. ns = non-significant, * P < 0.05, ** P < 0.01, *** P < 0.001. F Receiver operator curve of each hematologic parameter in MIS-C compared to values obtained from children presenting for medical care for infection/inflammatory or non-infectious illness

MDW depends on MIS-C severity and changes through the course of MIS-C diagnosis, treatment, and recovery. A Higher MDW values in MIS-C patients who manifested cardiac complications (Cardiac MIS-C) compared to children with MIS-C without cardiac involvement or presenting with symptoms concerning MIS-C (fever plus recent/current positive SARS-CoV2 PCR or SARS-CoV2 antibodies positive). B ROC in the validation cohort to assess the utility of MDW as a screening tool for cardiac involvement of MIS-C. AUC = area under the curve (fraction). C Blood from children with MIS-C was collected at multiple time points. MDW was plotted by time of collection: at admission, during hospital course, and at discharge or follow-up. Analysis by one way ANOVA. **P < 0.01, ****P < 0.0001. D MDW values from individual patients with MIS-C are plotted over the course of their illness. Black lines connect individual patients with MIS-C. Not all patients provided blood samples at each time point Assessment of other hematological parameters in MIS-C. Hematologic parameters, including A white blood cell (WBC), B neutrophil (PMN), C lymphocyte, D monocyte, and E platelet counts were compared between healthy controls, children with non-infectious illness, children with an infectious/inflammatory illness, and children with MIS-C in the validation cohort. Analysis by ordinary one-way ANOVA. ns = non-significant, * P < 0.05, ** P < 0.01, *** P < 0.001. F Receiver operator curve of each hematologic parameter in MIS-C compared to values obtained from children presenting for medical care for infection/inflammatory or non-infectious illness The original article has been corrected.
  1 in total

1.  Monocyte anisocytosis increases during multisystem inflammatory syndrome in children with cardiovascular complications.

Authors:  Lael M Yonker; Oluwakemi Badaki-Makun; Puneeta Arya; Brittany P Boribong; Gabriela Moraru; Brittany Fenner; Jaimar Rincon; Alex Hopke; Brent Rogers; Jeremiah Hinson; Alessio Fasano; Lilly Lee; Sarah M Kehoe; Shawn D Larson; Hector Chavez; Scott Levin; Lyle L Moldawer; Daniel Irimia
Journal:  BMC Infect Dis       Date:  2022-06-20       Impact factor: 3.667

  1 in total

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