Literature DB >> 35796775

Applications of artificial intelligence multiomics in precision oncology.

Ruby Srivastava1.   

Abstract

Cancer is the second leading worldwide disease that depends on oncogenic mutations and non-mutated genes for survival. Recent advancements in next-generation sequencing (NGS) have transformed the health care sector with big data and machine learning (ML) approaches. NGS data are able to detect the abnormalities and mutations in the oncogenes. These multi-omics analyses are used for risk prediction, early diagnosis, accurate prognosis, and identification of biomarkers in cancer patients. The availability of these cancer data and their analysis may provide insights into the biology of the disease, which can be used for the personalized treatment of cancer patients. Bioinformatics tools are delivering this promise by managing, integrating, and analyzing these complex datasets. The clinical outcomes of cancer patients are improved by the use of various innovative methods implicated particularly for diagnosis and therapeutics. ML-based artificial intelligence (AI) applications are solving these issues to a great extent. AI techniques are used to update the patients on a personalized basis about their treatment procedures, progress, recovery, therapies used, dietary changes in lifestyles patterns along with the survival summary of previously recovered cancer patients. In this way, the patients are becoming more aware of their diseases and the entire clinical treatment procedures. Though the technology has its own advantages and disadvantages, we hope that the day is not so far when AI techniques will provide personalized treatment to cancer patients tailored to their needs in much quicker ways.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Artificial intelligence; Cancer; Drugs; Machine learning; Next-generation sequencing

Year:  2022        PMID: 35796775     DOI: 10.1007/s00432-022-04161-4

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN: 0171-5216            Impact factor:   4.553


  33 in total

Review 1.  Proteomics: Technologies and Their Applications.

Authors:  Bilal Aslam; Madiha Basit; Muhammad Atif Nisar; Mohsin Khurshid; Muhammad Hidayat Rasool
Journal:  J Chromatogr Sci       Date:  2016-10-18       Impact factor: 1.618

2.  Next-Generation Implementation of Chimeric Antigen Receptor T-Cell Therapy Using Digital Health.

Authors:  Rahul Banerjee; Nina Shah; Adam P Dicker
Journal:  JCO Clin Cancer Inform       Date:  2021-06

3.  A machine learning approach for predicting CRISPR-Cas9 cleavage efficiencies and patterns underlying its mechanism of action.

Authors:  Shiran Abadi; Winston X Yan; David Amar; Itay Mayrose
Journal:  PLoS Comput Biol       Date:  2017-10-16       Impact factor: 4.475

4.  Artificial intelligence (AI) in healthcare and biomedical research: Why a strong computational/AI bioethics framework is required?

Authors:  Jatinder Bali; Rohit Garg; Renu T Bali
Journal:  Indian J Ophthalmol       Date:  2019-01       Impact factor: 1.848

5.  MAV-clic: management, analysis, and visualization of clinical data.

Authors:  Zeeshan Ahmed; Minjung Kim; Bruce T Liang
Journal:  JAMIA Open       Date:  2018-12-29

Review 6.  Machine Learning: A New Prospect in Multi-Omics Data Analysis of Cancer.

Authors:  Babak Arjmand; Shayesteh Kokabi Hamidpour; Akram Tayanloo-Beik; Parisa Goodarzi; Hamid Reza Aghayan; Hossein Adibi; Bagher Larijani
Journal:  Front Genet       Date:  2022-01-27       Impact factor: 4.599

7.  How many human proteoforms are there?

Authors:  Ruedi Aebersold; Jeffrey N Agar; I Jonathan Amster; Mark S Baker; Carolyn R Bertozzi; Emily S Boja; Catherine E Costello; Benjamin F Cravatt; Catherine Fenselau; Benjamin A Garcia; Ying Ge; Jeremy Gunawardena; Ronald C Hendrickson; Paul J Hergenrother; Christian G Huber; Alexander R Ivanov; Ole N Jensen; Michael C Jewett; Neil L Kelleher; Laura L Kiessling; Nevan J Krogan; Martin R Larsen; Joseph A Loo; Rachel R Ogorzalek Loo; Emma Lundberg; Michael J MacCoss; Parag Mallick; Vamsi K Mootha; Milan Mrksich; Tom W Muir; Steven M Patrie; James J Pesavento; Sharon J Pitteri; Henry Rodriguez; Alan Saghatelian; Wendy Sandoval; Hartmut Schlüter; Salvatore Sechi; Sarah A Slavoff; Lloyd M Smith; Michael P Snyder; Paul M Thomas; Mathias Uhlén; Jennifer E Van Eyk; Marc Vidal; David R Walt; Forest M White; Evan R Williams; Therese Wohlschlager; Vicki H Wysocki; Nathan A Yates; Nicolas L Young; Bing Zhang
Journal:  Nat Chem Biol       Date:  2018-02-14       Impact factor: 15.040

8.  Deep Learning Applications for Predicting Pharmacological Properties of Drugs and Drug Repurposing Using Transcriptomic Data.

Authors:  Alexander Aliper; Sergey Plis; Artem Artemov; Alvaro Ulloa; Polina Mamoshina; Alex Zhavoronkov
Journal:  Mol Pharm       Date:  2016-06-08       Impact factor: 4.939

9.  'Isotopo' a database application for facile analysis and management of mass isotopomer data.

Authors:  Zeeshan Ahmed; Saman Zeeshan; Claudia Huber; Michael Hensel; Dietmar Schomburg; Richard Münch; Eva Eylert; Wolfgang Eisenreich; Thomas Dandekar
Journal:  Database (Oxford)       Date:  2014-09-09       Impact factor: 3.451

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