| Literature DB >> 35796000 |
Justin Meskas1, Daniel Yokosawa1, Sherrie Wang1,2, Gabriela C Segat1, Ryan Remy Brinkman1,3.
Abstract
Technical artifacts such as clogging that occur during the data acquisition process of flow cytometry data can cause spurious events and fluorescence intensity shifting that impact the quality of the data and its analysis results. These events should be identified and potentially removed before being passed to the next stage of analysis. flowCut, an R package, automatically detects anomaly events in flow cytometry experiments and flags files for potential review. Its results are on par with manual analysis and it outperforms existing automated approaches.Entities:
Keywords: anomaly detection; bioinformatics; data acquisition; data cleaning; flow cytometry; outlier detection; quality checking
Year: 2022 PMID: 35796000 DOI: 10.1002/cyto.a.24670
Source DB: PubMed Journal: Cytometry A ISSN: 1552-4922 Impact factor: 4.714