Ryan J Emenecker1,2, Alex S Holehouse3,4. 1. Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA. 2. Center for Science and Engineering Living Systems (CSELS), Washington University, St. Louis, MO, USA. 3. Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA. alex.holehouse@wustl.edu. 4. Center for Science and Engineering Living Systems (CSELS), Washington University, St. Louis, MO, USA. alex.holehouse@wustl.edu.