Introduction: The emergence of the coronavirus disease 2019 (COVID-19) pandemic has significantly impacted the globe. Understanding the association between the population's demographical, clinical risk factors, and outcome of COVID-19 is essential for healthcare providers to develop guidelines and future care plans. This study reports all diagnosed COVID-19 and admitted to Johns Hopkins Aramco Healthcare (JHAH) for hospitalization from March to July 2020. Methods: This is a retrospective study that presents the demographic, epidemiological, clinical, laboratory, and imaging characteristics of our patients and determines risk factors contributing to their COVID-19 outcome. Results: The study included 656 patients (53% were male, 60% were older than 50 years of age, 87% were Saudi nationals, 5% pregnant, and 92% non-smokers patients). The source of infection was mostly unknown to the patient or healthcare provider (58%), followed by contact transmission (36%) and travel (5%). In addition, we found that the vast majority of hospitalized patients presented with symptoms (76%) with (90.4%) mild to moderate symptoms and have had stable hospital course during their hospitalization (82.1%). Over fifty percent of the patients had abnormal x-ray upon admission, (4.7%) were intubated, (20.3%) were admitted to an intensive care unit (ICU) or a step-down unit (SDU), and finally (5.3%) were deceased. Conclusion: The majority of the patients in this study had mild disease, and their outcome was associated with some chronic diseases, most significantly hypertension. However, the study did not demonstrate a statistically significant association between smoking and obesity and COVID-19 outcomes.
Introduction: The emergence of the coronavirus disease 2019 (COVID-19) pandemic has significantly impacted the globe. Understanding the association between the population's demographical, clinical risk factors, and outcome of COVID-19 is essential for healthcare providers to develop guidelines and future care plans. This study reports all diagnosed COVID-19 and admitted to Johns Hopkins Aramco Healthcare (JHAH) for hospitalization from March to July 2020. Methods: This is a retrospective study that presents the demographic, epidemiological, clinical, laboratory, and imaging characteristics of our patients and determines risk factors contributing to their COVID-19 outcome. Results: The study included 656 patients (53% were male, 60% were older than 50 years of age, 87% were Saudi nationals, 5% pregnant, and 92% non-smokers patients). The source of infection was mostly unknown to the patient or healthcare provider (58%), followed by contact transmission (36%) and travel (5%). In addition, we found that the vast majority of hospitalized patients presented with symptoms (76%) with (90.4%) mild to moderate symptoms and have had stable hospital course during their hospitalization (82.1%). Over fifty percent of the patients had abnormal x-ray upon admission, (4.7%) were intubated, (20.3%) were admitted to an intensive care unit (ICU) or a step-down unit (SDU), and finally (5.3%) were deceased. Conclusion: The majority of the patients in this study had mild disease, and their outcome was associated with some chronic diseases, most significantly hypertension. However, the study did not demonstrate a statistically significant association between smoking and obesity and COVID-19 outcomes.
Authors: Francesco Rubino; Stephanie A Amiel; Paul Zimmet; George Alberti; Stefan Bornstein; Robert H Eckel; Geltrude Mingrone; Bernhard Boehm; Mark E Cooper; Zhonglin Chai; Stefano Del Prato; Linong Ji; David Hopkins; William H Herman; Kamlesh Khunti; Jean-Claude Mbanya; Eric Renard Journal: N Engl J Med Date: 2020-06-12 Impact factor: 91.245
Authors: Rodrigo B Serafim; Pedro Póvoa; Vicente Souza-Dantas; André C Kalil; Jorge I F Salluh Journal: Clin Microbiol Infect Date: 2020-10-23 Impact factor: 8.067
Authors: Lennard Y W Lee; Jean-Baptiste Cazier; Thomas Starkey; Sarah E W Briggs; Roland Arnold; Vartika Bisht; Stephen Booth; Naomi A Campton; Vinton W T Cheng; Graham Collins; Helen M Curley; Philip Earwaker; Matthew W Fittall; Spyridon Gennatas; Anshita Goel; Simon Hartley; Daniel J Hughes; David Kerr; Alvin J X Lee; Rebecca J Lee; Siow Ming Lee; Hayley Mckenzie; Chris P Middleton; Nirupa Murugaesu; Tom Newsom-Davis; Anna C Olsson-Brown; Claire Palles; Thomas Powles; Emily A Protheroe; Karin Purshouse; Archana Sharma-Oates; Shivan Sivakumar; Ashley J Smith; Oliver Topping; Chris D Turnbull; Csilla Várnai; Adam D M Briggs; Gary Middleton; Rachel Kerr Journal: Lancet Oncol Date: 2020-08-24 Impact factor: 41.316
Authors: Hannah Peckham; Nina M de Gruijter; Charles Raine; Anna Radziszewska; Coziana Ciurtin; Lucy R Wedderburn; Elizabeth C Rosser; Kate Webb; Claire T Deakin Journal: Nat Commun Date: 2020-12-09 Impact factor: 17.694