Literature DB >> 35781675

Managing Behavioral and Psychological Symptoms of Dementia (BPSD) in the Era of Boxed Warnings.

Rajesh R Tampi1,2,3,4,5, Gargi Bhattacharya6, Padmapriya Marpuri7.   

Abstract

PURPOSE OF REVIEW: To provide a comprehensive overview on the evaluation and management of behavioral and psychological symptoms of dementia (BPSD) using evidence from literature. RECENT
FINDINGS: Evidence indicates efficacy for some non-pharmacological techniques including education of caregivers and cognitive stimulation therapy and pharmacological agents like antidepressant and antipsychotics for the management of BPSD. The use of antipsychotics has generated controversy due to the recognition of their serious adverse effect profile including the risk of cerebrovascular adverse events and death. BPSD is associated with worsening of cognition and function among individuals with dementia, greater caregiver burden, more frequent institutionalization, overall poorer quality of life, and greater cost of caring for these individuals. Future management strategies for BPSD should include the use of technology for the provision of non-pharmacological interventions and the judicious use of cannabinoids and interventional procedures like ECT for the management of refractory symptoms.
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Behavioral and psychological symptoms of dementia (BPSD); Cannabinoids; Electroconvulsive therapy (ECT); Neuropsychiatric inventory (NPI); Neuropsychiatric symptoms (NPS); Non-pharmacological management; Pharmacological strategies

Mesh:

Substances:

Year:  2022        PMID: 35781675     DOI: 10.1007/s11920-022-01347-y

Source DB:  PubMed          Journal:  Curr Psychiatry Rep        ISSN: 1523-3812            Impact factor:   8.081


  72 in total

1.  Prevalence and pharmacological management of behavioural and psychological symptoms amongst dementia sufferers living in care environments.

Authors:  M Margallo-Lana; A Swann; J O'Brien; A Fairbairn; K Reichelt; D Potkins; P Mynt; C Ballard
Journal:  Int J Geriatr Psychiatry       Date:  2001-01       Impact factor: 3.485

Review 2.  Delusions and hallucinations in Alzheimer's disease: review of the brain decade.

Authors:  Medhat M Bassiony; Constantine G Lyketsos
Journal:  Psychosomatics       Date:  2003 Sep-Oct       Impact factor: 2.386

3.  Assessment of behavioral and psychological symptoms of dementia.

Authors:  A J Bharucha; J Rosen; B H Mulsant; B G Pollock
Journal:  CNS Spectr       Date:  2002-11       Impact factor: 3.790

4.  Mental and behavioral disturbances in dementia: findings from the Cache County Study on Memory in Aging.

Authors:  C G Lyketsos; M Steinberg; J T Tschanz; M C Norton; D C Steffens; J C Breitner
Journal:  Am J Psychiatry       Date:  2000-05       Impact factor: 18.112

Review 5.  Provisional diagnostic criteria for depression of Alzheimer disease: rationale and background.

Authors:  Jason T Olin; Ira R Katz; Barnett S Meyers; Lon S Schneider; Barry D Lebowitz
Journal:  Am J Geriatr Psychiatry       Date:  2002 Mar-Apr       Impact factor: 4.105

6.  The course of psychopathologic features in mild to moderate Alzheimer disease.

Authors:  D P Devanand; D M Jacobs; M X Tang; C Del Castillo-Castaneda; M Sano; K Marder; K Bell; F W Bylsma; J Brandt; M Albert; Y Stern
Journal:  Arch Gen Psychiatry       Date:  1997-03

Review 7.  Depression in Alzheimer's disease: heterogeneity and related issues.

Authors:  Hochang B Lee; Constantine G Lyketsos
Journal:  Biol Psychiatry       Date:  2003-08-01       Impact factor: 13.382

8.  The spectrum of behavioral changes in Alzheimer's disease.

Authors:  M S Mega; J L Cummings; T Fiorello; J Gornbein
Journal:  Neurology       Date:  1996-01       Impact factor: 9.910

9.  The evolution of psychiatric symptoms in Alzheimer's disease: a natural history study.

Authors:  B C Jost; G T Grossberg
Journal:  J Am Geriatr Soc       Date:  1996-09       Impact factor: 5.562

Review 10.  Depression in Alzheimer's disease: overview and treatment.

Authors:  Constantine G Lyketsos; Jason Olin
Journal:  Biol Psychiatry       Date:  2002-08-01       Impact factor: 13.382

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