Literature DB >> 35779102

Comparison of silver-embedded occlusive dressings and negative pressure wound therapy following total joint arthroplasty in high BMI patients: a randomized controlled trial.

Katherine A Lygrisse1, Greg Teo2, Vivek Singh3, Nishanth Muthusamy4,5, Ran Schwarzkopf3, Long William2.   

Abstract

INTRODUCTION: High body mass index (BMI) and wound drainage following total joint arthroplasty (TJA) can lead to wound healing complications and periprosthetic joint infection. Silver-embedded occlusive dressings and negative pressure wound therapy (NPWT) have been shown to reduce these complications. The purpose of this prospective trial was to compare the effect of silver-embedded dressings and NPWT on wound complications in patients with BMI ≥ 35 m/kg2 undergoing TJA.
METHODS: We conducted a randomized control trial of patients who had a BMI > 35 m/kg2 and were undergoing primary TJA between October 2017 and February 2020. Patients who underwent revision surgery, or those with an active infection, previous scar, history of wound healing complications, post-traumatic degenerative joint disease with hardware, or inflammatory arthritis were excluded. Patients were randomized to receive either a silver-embedded occlusive dressing (control) or NPWT. Frequency distributions, means, and standard deviations were used to describe patient demographics, postoperative complications, 90-day readmissions, and reoperations. T-test and chi-squared tests were used to test for significant differences between continuous and categorical variables, respectively.
RESULTS: Two hundred-thirty patients with 3-month follow-up were included. One-hundred-fifteen patients received the control and 115 patients received NPWT. There were six patients (5.2%) in the control group with wound complications (drainage: n = 5, non-healing wound: n = 1) and two patients (1.7%) in the NPWT with complications (drainage: n = 2). There were no 90-day readmissions in the control group versus two (1.8%) 90-day readmissions in the NPWT group. Finally, three patients (2.6%) in the control group underwent reoperations (irrigation and debridement [I&D], I&D with modular implant exchange, and implant revision), while none in the NPWT group had undergone reoperation. The two groups showed insignificant differences in wound complications (p = 0.28), 90-day readmissions (p = 0.50), and reoperations (p = 0.25).
CONCLUSION: Patients with BMI ≥ 35 m/kg2 undergoing TJA have no statistical difference in early wound complications, readmissions, or reoperations when treated with either silver-embedded dressings or NPWT.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Negative pressure wound therapy; Obesity; Prosthetic joint infection; Total joint arthroplasty; Wound complications; Wound dressing

Year:  2022        PMID: 35779102     DOI: 10.1007/s00402-022-04530-1

Source DB:  PubMed          Journal:  Arch Orthop Trauma Surg        ISSN: 0936-8051            Impact factor:   2.928


  22 in total

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Authors:  Jenny Cai; Joseph A Karam; Javad Parvizi; Eric B Smith; Peter F Sharkey
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4.  Closed-Incision Negative-Pressure Therapy Versus Antimicrobial Dressings After Revision Hip and Knee Surgery: A Comparative Study.

Authors:  H John Cooper; Marcel A Bas
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Authors:  Stephen Yu; Matthew Siow; Khalid Odeh; William J Long; Ran Schwarzkopf; Richard Iorio
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8.  Morbidly obese, diabetic, younger, and unilateral joint arthroplasty patients have elevated total joint arthroplasty infection rates.

Authors:  Robert A Malinzak; Merrill A Ritter; Michael E Berend; John B Meding; Emily M Olberding; Kenneth E Davis
Journal:  J Arthroplasty       Date:  2009-07-15       Impact factor: 4.757

9.  Risk and Cost of 90-Day Complications in Morbidly and Superobese Patients After Total Knee Arthroplasty.

Authors:  Menachem M Meller; Nader Toossi; Norman A Johanson; Mark H Gonzalez; Min-Sun Son; Edmund C Lau
Journal:  J Arthroplasty       Date:  2016-03-10       Impact factor: 4.757

10.  Factors associated with osteoarthritis of the knee in the first national Health and Nutrition Examination Survey (HANES I). Evidence for an association with overweight, race, and physical demands of work.

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Journal:  Am J Epidemiol       Date:  1988-07       Impact factor: 4.897

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