Literature DB >> 3577435

[Fatal poisoning by protriptyline and haloperidol following an extreme overdose].

G Fechner, I Magureanu, R Aderjan, G Schmidt.   

Abstract

In this paper the authors report on a case of lethal suicidal toxification with protriptyline and haloperidol after oral ingestion. Gas chromatographic and radioimmunologic investigations were used for quantitative determination of protriptyline and haloperidol in blood, urine, and tissues. The highest concentrations were found in lung and liver. These concentrations are discussed with reference to the cause of death.

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Year:  1986        PMID: 3577435     DOI: 10.1007/bf00200607

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN: 0044-3433


  16 in total

1.  Psychoactive drug interactions.

Authors:  C T Gaultieri; S F Powell
Journal:  J Clin Psychiatry       Date:  1978-09       Impact factor: 4.384

2.  [Determination of amitriptyline and metabolites in various organs after fatal poisoning].

Authors:  U Breyer; H Remmer
Journal:  Arch Toxikol       Date:  1971

3.  Studies of C-14-protriptyline man: plasma levels and excretion.

Authors:  K D Charalampous; P C Johnson
Journal:  J Clin Pharmacol J New Drugs       Date:  1967 Mar-Apr

4.  Pharmacokinetic aspects of protriptyline plasma levels.

Authors:  J P Moody; S F Whyte; A J MacDonald; G J Naylor
Journal:  Eur J Clin Pharmacol       Date:  1977       Impact factor: 2.953

5.  Sudden death in a patient taking haloperidol.

Authors:  R Ketai; J Matthews; J J Mozdzen
Journal:  Am J Psychiatry       Date:  1979-01       Impact factor: 18.112

6.  Toxicology of some autopsy cases involving tricyclic antidepressant drugs.

Authors:  A E Robinson; A I Coffer; R D McDowall
Journal:  Z Rechtsmed       Date:  1974

7.  Interaction between antidepressants and perphenazine in psychiatric inpatients.

Authors:  M Linnoila; L George; S Guthrie
Journal:  Am J Psychiatry       Date:  1982-10       Impact factor: 18.112

8.  Blood and tissue concentrations of tricyclic antidepressant drugs in post mortem cases: literature survey and a study of forty deaths.

Authors:  J H Hebb; Y H Caplan; C R Crooks; W J Mergner
Journal:  J Anal Toxicol       Date:  1982 Sep-Oct       Impact factor: 3.367

9.  Blood levels of neuroleptic drugs in nonresponding chronic schizophrenic patients.

Authors:  R C Smith; J Crayton; H Dekirmenjian; D Klass; J M Davis
Journal:  Arch Gen Psychiatry       Date:  1979-05

10.  Plasma concentrations of protriptyline and clinical effects in depressed women.

Authors:  S F Whyte; A J Macdonald; G J Naylor; J P Moody
Journal:  Br J Psychiatry       Date:  1976-04       Impact factor: 9.319

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