Literature DB >> 35774327

Dual-wavelength multimodal multiphoton microscope with SMA-based depth scanning.

Wentao Wu1,2, Qihao Liu1, Christoph Brandt1, Shuo Tang1,3.   

Abstract

We report on a multimodal multiphoton microscopy (MPM) system with depth scanning. The multimodal capability is realized by an Er-doped femtosecond fiber laser with dual output wavelengths of 1580 nm and 790 nm that are responsible for three-photon and two-photon excitation, respectively. A shape-memory-alloy (SMA) actuated miniaturized objective enables the depth scanning capability. Image stacks combined with two-photon excitation fluorescence (TPEF), second harmonic generation (SHG), and third harmonic generation (THG) signals have been acquired from animal, fungus, and plant tissue samples with a maximum depth range over 200 µm.
© 2022 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement.

Entities:  

Year:  2022        PMID： 35774327      PMCID： PMC9203102          DOI： 10.1364/BOE.456390

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN： 2156-7085            Impact factor:   3.562


  48 in total

1.  High-resolution nonlinear optical imaging of live cells by second harmonic generation.

Authors:  P J Campagnola; M D Wei; A Lewis; L M Loew
Journal:  Biophys J       Date:  1999-12       Impact factor: 4.033

2.  Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation.

Authors:  Warren R Zipfel; Rebecca M Williams; Richard Christie; Alexander Yu Nikitin; Bradley T Hyman; Watt W Webb
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-19       Impact factor: 11.205

3.  Cell lineage reconstruction of early zebrafish embryos using label-free nonlinear microscopy.

Authors:  Nicolas Olivier; Miguel A Luengo-Oroz; Louise Duloquin; Emmanuel Faure; Thierry Savy; Israël Veilleux; Xavier Solinas; Delphine Débarre; Paul Bourgine; Andrés Santos; Nadine Peyriéras; Emmanuel Beaurepaire
Journal:  Science       Date:  2010-08-20       Impact factor: 47.728

4.  Label-free multi-photon imaging of dysplasia in Barrett's esophagus.

Authors:  Soroush Mehravar; Bhaskar Banerjee; Hemant Chatrath; Babak Amirsolaimani; Krunal Patel; Charmi Patel; Robert A Norwood; Nasser Peyghambarian; Khanh Kieu
Journal:  Biomed Opt Express       Date:  2015-12-16       Impact factor: 3.732

5.  Focus scanning with feedback-control for fiber-optic nonlinear endomicroscopy.

Authors:  Ang Li; Wenxuan Liang; Honghua Guan; Yung-Tian A Gau; Dwight E Bergles; Xingde Li
Journal:  Biomed Opt Express       Date:  2017-04-17       Impact factor: 3.732

6.  Two-photon laser scanning fluorescence microscopy.

Authors:  W Denk; J H Strickler; W W Webb
Journal:  Science       Date:  1990-04-06       Impact factor: 47.728

7.  Miniaturized multimodal multiphoton microscope for simultaneous two-photon and three-photon imaging with a dual-wavelength Er-doped fiber laser.

Authors:  Lin Huang; Xin Zhou; Qihao Liu; Calum E MacAulay; Shuo Tang
Journal:  Biomed Opt Express       Date:  2020-01-06       Impact factor: 3.732

8.  Third Harmonic Generation microscopy as a reliable diagnostic tool for evaluating lipid body modification during cell activation: the example of BV-2 microglia cells.

Authors:  E Gavgiotaki; G Filippidis; M Kalognomou; A A Tsouko; I Skordos; C Fotakis; I Athanassakis
Journal:  J Struct Biol       Date:  2014-12-05       Impact factor: 2.867

9.  Third harmonic generation imaging for fast, label-free pathology of human brain tumors.

Authors:  N V Kuzmin; P Wesseling; P C de Witt Hamer; D P Noske; G D Galgano; H D Mansvelder; J C Baayen; M L Groot
Journal:  Biomed Opt Express       Date:  2016-04-18       Impact factor: 3.732

10.  Multiphoton imaging of neural structure and activity in Drosophila through the intact cuticle.

Authors:  Max Jameson Aragon; Aaron T Mok; Jamien Shea; Mengran Wang; Haein Kim; Nathan Barkdull; Chris Xu; Nilay Yapici
Journal:  Elife       Date:  2022-01-24       Impact factor: 8.140
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