Hu Chen1,2, Changrong Zhu1,2, Honglei Yi1,2, Hao Sun2, Xiangyang Ma1,2, Jianhua Wang1,2, Kai Zhang2, Fuzhi Ai3, Zenghui Wu2, Qingshui Yin2, Qiang Tu4,5, Hong Xia6,7. 1. The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China. 2. Department of Orthopedic, People's Liberation Army General Hospital of Southern Theatre Command, Guangzhou, Guangdong, China. 3. Department of Orthopedic, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. 4. The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China. tuqiang@126.com. 5. Department of Orthopedic, People's Liberation Army General Hospital of Southern Theatre Command, Guangzhou, Guangdong, China. tuqiang@126.com. 6. The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China. gzxiahong2@126.com. 7. Department of Orthopedic, People's Liberation Army General Hospital of Southern Theatre Command, Guangzhou, Guangdong, China. gzxiahong2@126.com.
Abstract
PURPOSE: Transoral approach can accomplish ventral decompression directly. However, surgical site infection (SSI) cannot be ignored. This paper aims to review the prevalence of infection and conduct advice for the treatment of SSI in the cervical spine following the transoral approach. METHODS: A retrospective analysis of patients with SSI after transoral atlantoaxial reduction plate (TARP) surgery was performed. SSI was classified into three kinds according to the modified American CDC criteria. RESULTS: 2.9% (17/581) patients who underwent TARP surgery, experienced SSI, of which five had superficial SSI (SI), eight had deep SSI (DI), and four had organ/space SSI (O/SI). The patients with SI underwent intravenous antibiotic treatment and were ultimately cured. Among the remaining 12 patients with DI and O/SI, 11 underwent reoperation for TARP system removal and subsequently one-stage posterior occipitocervical fixation, and one patient experienced infection two months post-operatively and died without receiving treatment. Among patients who underwent revision surgery, three experienced intracranial infection due to intra-operative dural tears, and continuous lumbar cerebrospinal fluid drainage and intrathecal injection of antibiotics were used as effective and appropriate treatments, with outcomes of one recovery and two deaths. All patients with SSI were begun on intravenous antibiotics with conversion to oral antibiotics. CONCLUSIONS: The incidence of SSI was 2.9% (17/581). Adequate peri-operative preparation, early diagnosis, and appropriate treatment of SSI require further research.
PURPOSE: Transoral approach can accomplish ventral decompression directly. However, surgical site infection (SSI) cannot be ignored. This paper aims to review the prevalence of infection and conduct advice for the treatment of SSI in the cervical spine following the transoral approach. METHODS: A retrospective analysis of patients with SSI after transoral atlantoaxial reduction plate (TARP) surgery was performed. SSI was classified into three kinds according to the modified American CDC criteria. RESULTS: 2.9% (17/581) patients who underwent TARP surgery, experienced SSI, of which five had superficial SSI (SI), eight had deep SSI (DI), and four had organ/space SSI (O/SI). The patients with SI underwent intravenous antibiotic treatment and were ultimately cured. Among the remaining 12 patients with DI and O/SI, 11 underwent reoperation for TARP system removal and subsequently one-stage posterior occipitocervical fixation, and one patient experienced infection two months post-operatively and died without receiving treatment. Among patients who underwent revision surgery, three experienced intracranial infection due to intra-operative dural tears, and continuous lumbar cerebrospinal fluid drainage and intrathecal injection of antibiotics were used as effective and appropriate treatments, with outcomes of one recovery and two deaths. All patients with SSI were begun on intravenous antibiotics with conversion to oral antibiotics. CONCLUSIONS: The incidence of SSI was 2.9% (17/581). Adequate peri-operative preparation, early diagnosis, and appropriate treatment of SSI require further research.
Authors: Jeremy Steinberger; Branko Skovrlj; Nathan J Lee; Parth Kothari; Dante M Leven; Javier Z Guzman; John Shin; Raj Shrivastava; John M Caridi; Samuel K Cho Journal: Spine (Phila Pa 1976) Date: 2016-05 Impact factor: 3.468
Authors: Aditya V Karhade; Viren S Vasudeva; Hormuzdiyar H Dasenbrock; Yi Lu; William B Gormley; Michael W Groff; John H Chi; Timothy R Smith Journal: Neurosurg Focus Date: 2016-08 Impact factor: 4.047