Literature DB >> 3576639

Production of tetrodotoxin and its derivatives by Pseudomonas sp. isolated from the skin of a pufferfish.

M Yotsu, T Yamazaki, Y Meguro, A Endo, M Murata, H Naoki, T Yasumoto.   

Abstract

Bacteria isolated from the skin of the pufferfish Fugu poecilonotus were screened for tetrodotoxin production. Tetrodotoxin and its derivatives were detected by HPLC analyses in broth cultures of a Pseudomonas sp. Upon alkali treatment the compounds yielded, as do tetrodotoxin and its derivatives, 2-amino-6-hydroxymethyl-8-hydroxyquinazoline, the identity of which was confirmed, after methylation or trimethylsilylation, by HPLC, mass spectrometry and gas chromatography - mass spectrometry.

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Year:  1987        PMID： 3576639     DOI： 10.1016/0041-0101(87)90245-5

Source DB:  PubMed          Journal:  Toxicon        ISSN： 0041-0101            Impact factor:   3.033


  19 in total

Review 1.  Avian chemical defense: toxic birds not of a feather.

Authors:  P J Weldon
Journal:  Proc Natl Acad Sci U S A       Date:  2000-11-21       Impact factor: 11.205

Review 2.  Properties and use of botulinum toxin and other microbial neurotoxins in medicine.

Authors:  E J Schantz; E A Johnson
Journal:  Microbiol Rev       Date:  1992-03

3.  A marine Micrococcus produces metabolites ascribed to the sponge Tedania ignis.

Authors:  A C Stierle; J H Cardellina; F L Singleton
Journal:  Experientia       Date:  1988-12-01

4.  Purification and characterization of a novel antibacterial protein from the marine bacterium D2.

Authors:  S G James; C Holmström; S Kjelleberg
Journal:  Appl Environ Microbiol       Date:  1996-08       Impact factor: 4.792

5.  Protection against nerve toxicity by monoclonal antibodies to the sodium channel blocker tetrodotoxin.

Authors:  R I Huot; D L Armstrong; T C Chanh
Journal:  J Clin Invest       Date:  1989-06       Impact factor: 14.808

6.  Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus.

Authors:  Mandë Holford; Min-Min Zhang; K Hanumae Gowd; Layla Azam; Brad R Green; Maren Watkins; John-Paul Ownby; Doju Yoshikami; Grzegorz Bulaj; Baldomero M Olivera
Journal:  Toxicon       Date:  2008-11-20       Impact factor: 3.033

7.  Reexamination of tetrodotoxin production by bacteria.

Authors:  K Matsumura
Journal:  Appl Environ Microbiol       Date:  1995-09       Impact factor: 4.792

8.  On the evolutionary significance of the size and planarity of the proline ring.

Authors:  Jörn Behre; Roland Voigt; Ingo Althöfer; Stefan Schuster
Journal:  Naturwissenschaften       Date:  2012-09-15

9.  New gastropod vectors and tetrodotoxin potential expansion in temperate waters of the Atlantic Ocean.

Authors:  Marisa Silva; Joana Azevedo; Paula Rodriguez; Amparo Alfonso; Luis M Botana; Vítor Vasconcelos
Journal:  Mar Drugs       Date:  2012-03-26       Impact factor: 6.085

10.  Isolation and identification of a new tetrodotoxin-producing bacterial species, Raoultella terrigena, from Hong Kong marine puffer fish Takifugu niphobles.

Authors:  Vincent Chung-Him Yu; Peter Hoi-Fu Yu; Kin-Chung Ho; Fred Wang-Fat Lee
Journal:  Mar Drugs       Date:  2011-11-14       Impact factor: 6.085
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