IgD myeloma with malignant pleural effusion.

We have described a patient with IgD myeloma and pleural effusions in whom biopsy and postmortem examination demonstrated myelomatous pleural involvement with IgD-positive plasma cells. Despite the presence of two uniformly poor prognostic features (IgD type and malignant effusion) at presentation, this patient survived for two years. This is the first case of IgD myeloma with documented malignant pleural effusion reported in the English literature.