Literature DB >> 35761142

A facile one-pot synthesis of new functionalized pyrazolone-1,4-dithiafulvene hybrids.

Jaber Salehzadeh1, Farough Nasiri2.   

Abstract

In this study, a one-pot reaction between β-keto esters or dialkyl acetylenedicarboxylates with hydrazines, carbon disulfide, and dialkyl acetylenedicarboxylates in the presence of triethylamine is reported. This reaction proceeded at room temperature and was completed within 6 h to produce functionalized pyrazolone-1,4-dithiafulvene hybrids in good yields.
© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.

Entities:  

Keywords:  1,3-Dithiole; 1,4-Dithiafulvene; 5-Pyrazolone; Hybrid molecules; One-pot reaction

Year:  2022        PMID： 35761142     DOI： 10.1007/s11030-022-10473-x

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  10 in total

1.  Regioselective four-component synthesis of new tetrazolo[1,5-a]quinoline-based 2-amino-1,4-dihydropyridine and pyridin-2(1H)-one derivatives using nano-ZnO catalysis.

Authors:  Tooran Aghaalizadeh; Farough Nasiri
Journal:  Mol Divers       Date:  2018-06-27       Impact factor: 2.943

Review 2.  Role of sulphur-heterocycles in medicinal chemistry: An update.

Authors:  Shelly Pathania; Raj Kumar Narang; Ravindra K Rawal
Journal:  Eur J Med Chem       Date:  2019-07-15       Impact factor: 6.514

3.  Dithiafulvene derivatized donor-acceptor norbornadienes with redshifted absorption.

Authors:  Mads Mansø; Martin Drøhse Kilde; Sandeep Kumar Singh; Paul Erhart; Kasper Moth-Poulsen; Mogens Brøndsted Nielsen
Journal:  Phys Chem Chem Phys       Date:  2019-02-06       Impact factor: 3.676

4.  Novel Hybrids of Pyrazolidinedione and Benzothiazole as TZD Analogues. Rationale Design, Synthesis and In Vivo Anti-Diabetic Evaluation.

Authors:  Michelyne Haroun
Journal:  Med Chem       Date:  2019       Impact factor: 2.745

Review 5.  Hybrid molecules: The privileged scaffolds for various pharmaceuticals.

Authors:  Sahil Mishra; Palwinder Singh
Journal:  Eur J Med Chem       Date:  2016-08-21       Impact factor: 6.514

6.  Edaravone and benidipine protect myocardial damage by regulating mitochondrial stress, apoptosis signalling and cardiac biomarkers against doxorubicin-induced cardiotoxicity.

Authors:  Md Quamrul Hassan; Md Sayeed Akhtar; Obaid Afzal; Ibraheem Hussain; Mohd Akhtar; Syed Ehtaishamul Haque; Abul Kalam Najmi
Journal:  Clin Exp Hypertens       Date:  2019-10-20       Impact factor: 1.749

7.  Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies.

Authors:  Mohamed A Abdelgawad; Madlen B Labib; Waleed A M Ali; Gehan Kamel; Amany A Azouz; El-Shaymaa El-Nahass
Journal:  Bioorg Chem       Date:  2018-03-08       Impact factor: 5.275

8.  One-pot solvent-free three-component reaction between primary amines, carbon disulfide, and 5-alkylidene rhodanines: a convenient synthesis of asymmetric birhodanines.

Authors:  Farough Nasiri; Parisa Nazari
Journal:  Mol Divers       Date:  2018-03-15       Impact factor: 2.943

Review 9.  Pyrazolone structural motif in medicinal chemistry: Retrospect and prospect.

Authors:  Zefeng Zhao; Xufen Dai; Chenyang Li; Xiao Wang; Jiale Tian; Ying Feng; Jing Xie; Cong Ma; Zhuang Nie; Peinan Fan; Mingcheng Qian; Xirui He; Shaoping Wu; Yongmin Zhang; Xiaohui Zheng
Journal:  Eur J Med Chem       Date:  2019-11-16       Impact factor: 6.514

10.  Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors.

Authors:  R Ramajayam; Kian-Pin Tan; Hun-Ge Liu; Po-Huang Liang
Journal:  Bioorg Med Chem       Date:  2010-09-25       Impact factor: 3.641
  10 in total

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