Literature DB >> 35761103

Prevalence of constipation in patients undergoing chemotherapy and the effect of constipation on quality of life.

Zeynep Pehlivan1, Nesrin Nural2.   

Abstract

OBJECTIVE: This study was conducted as a descriptive and cross-sectional study to determine the prevalence of constipation and the impact of constipation on quality of life in patients receiving outpatient chemotherapy.
MATERIALS AND METHODS: The data of the study were collected from 252 patients who applied to the outpatient chemotherapy unit of a university hospital between January 2021 and March 2021. The data were collected using the "Patient Information Form," "Eastern Cooperative Oncology Group (ECOG) Performance Status Scale," "Constipation Severity Scale (CSS)," "Patient Assessment of Constipation Quality of Life Questionnaire (PAC-QOL)," and "The Bristol Stool Form Scale" through face-to-face interview technique. In the analysis of data, numbers, percentile distributions, minimum and maximum values, mean values, and standard deviations, as well as t-test, were used in the comparison of paired groups in normally distributed measurements, while the analysis of variance (ANOVA) was used in the comparison of more than two groups.
RESULTS: The constipation prevalence of the patients included in the study was 31.7% and the mean constipation severity score was 30.48 ± 13.87. It was found that the quality of life of the patients due to constipation was (71.79 ± 18.74) impacted adversely on a moderate level. A significant difference was found between sex, educational status, use of antiemetic and antiulcer medication, presence of hemorrhoid disease, ECOG score, appetite, and mean CSS and PAC-QOL scores (p < 0.05).
CONCLUSION: Constipation occurs in one-third of cancer patients receiving ambulatory chemotherapy. The severity of constipation in patients is at a moderate level and it impacts the quality of life moderately.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Cancer; Chemotherapy; Constipation; Patient; Quality of life

Mesh:

Substances:

Year:  2022        PMID: 35761103     DOI: 10.1007/s00520-022-07244-7

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.359


  15 in total

Review 1.  Prevalence of, and risk factors for, chronic idiopathic constipation in the community: systematic review and meta-analysis.

Authors:  Nicole C Suares; Alexander C Ford
Journal:  Am J Gastroenterol       Date:  2011-05-24       Impact factor: 10.864

Review 2.  Systematic review: impact of constipation on quality of life in adults and children.

Authors:  J Belsey; S Greenfield; D Candy; M Geraint
Journal:  Aliment Pharmacol Ther       Date:  2010-02-20       Impact factor: 8.171

3.  Predictors of the multidimensional symptom experience of lung cancer patients receiving chemotherapy.

Authors:  Melisa L Wong; Steven M Paul; Bruce A Cooper; Laura B Dunn; Marilyn J Hammer; Yvette P Conley; Fay Wright; Jon D Levine; Louise C Walter; Frances Cartwright; Christine Miaskowski
Journal:  Support Care Cancer       Date:  2017-02-03       Impact factor: 3.603

Review 4.  Impact of chemotherapy on gastrointestinal functions and the enteric nervous system.

Authors:  Jonathan Escalante; Rachel M McQuade; Vanesa Stojanovska; Kulmira Nurgali
Journal:  Maturitas       Date:  2017-05-10       Impact factor: 4.342

5.  Gastrointestinal symptoms and weight loss in cancer patients receiving chemotherapy.

Authors:  Karla Sánchez-Lara; Emilio Ugalde-Morales; Daniel Motola-Kuba; Dan Green
Journal:  Br J Nutr       Date:  2012-06-12       Impact factor: 3.718

6.  Development and validation of the Patient Assessment of Constipation Quality of Life questionnaire.

Authors:  Patrick Marquis; Christine De La Loge; Dominique Dubois; Anne McDermott; Olivier Chassany
Journal:  Scand J Gastroenterol       Date:  2005-05       Impact factor: 2.423

Review 7.  Management of thalidomide toxicity.

Authors:  Irene M Ghobrial; S Vincent Rajkumar
Journal:  J Support Oncol       Date:  2003 Sep-Oct

8.  Survey of laxative use by adults with self-defined constipation in South America and Asia: a comparison of six countries.

Authors:  A Wald; S Mueller-Lissner; M A Kamm; U Hinkel; E Richter; C Schuijt; K G Mandel
Journal:  Aliment Pharmacol Ther       Date:  2009-10-13       Impact factor: 8.171

9.  The constipation severity instrument: a validated measure.

Authors:  Madhulika G Varma; Jennifer Y Wang; Julia R Berian; Taryn R Patterson; G Lindsay McCrea; Stacey L Hart
Journal:  Dis Colon Rectum       Date:  2008-01-03       Impact factor: 4.585

10.  Effects of a self-management program on antiemetic-induced constipation during chemotherapy among breast cancer patients: a randomized controlled clinical trial.

Authors:  Akiko Hanai; Hiroshi Ishiguro; Takashi Sozu; Moe Tsuda; Hidenori Arai; Akira Mitani; Tadao Tsuboyama
Journal:  Breast Cancer Res Treat       Date:  2015-12-09       Impact factor: 4.872

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