Literature DB >> 35756830

Prevalence and Predictors of Lower Limb Amputation in the Spinal Cord Injury Population.

Tommy C Yu1,2, Morgan Pyne1,2, Brian Higdon2, Robert Rotman2, Rahul Mhaskar2.   

Abstract

Background: Despite limited data demonstrating altered hemodynamics in the lower extremities (LEs) among the population with spinal cord injury (SCI) and increased frequency of peripheral arterial disease (PAD), epidemiologic data are limited for amputations, a potential consequence. This study investigates the association of amputation due to vascular complications as a secondary outcome measure within the SCI population.
Methods: A retrospective cohort study was performed within a veteran population with SCI at a US Department of Veteran Affairs hospital to determine the prevalence of limb loss. We hypothesized that premorbid SCI increased the likelihood of LE amputation.
Results: Of 1055 charts reviewed, 91 (8.7%) patients had an amputation, 70 (76.1%) had a dysvascular etiology. Transfemoral amputations were the most common level (n = 53) of amputation. Our results showed a positive correlation between the completeness of injury and the prevalence of amputation.
Conclusion: There is an increased frequency of amputation among the veteran population with SCI compared with that of the general US population. Amputations frequently occur at more proximal levels with motor complete injuries. Studies using a larger population and multiple centers are needed to confirm this alarming trend.
Copyright © 2022 Frontline Medical Communications Inc., Parsippany, NJ, USA.

Entities:  

Year:  2022        PMID: 35756830      PMCID: PMC9217072          DOI: 10.12788/fp.0250

Source DB:  PubMed          Journal:  Fed Pract        ISSN: 1078-4497


  25 in total

Review 1.  Noninvasive assessment of arterial stiffness and risk of atherosclerotic events.

Authors:  James J Oliver; David J Webb
Journal:  Arterioscler Thromb Vasc Biol       Date:  2003-02-06       Impact factor: 8.311

Review 2.  Preventing amputation in the patient with diabetes.

Authors:  M E Levin
Journal:  Diabetes Care       Date:  1995-10       Impact factor: 19.112

3.  Diagnosis and treatment of peripheral arterial disease.

Authors:  Duane R Hennion; Kelly A Siano
Journal:  Am Fam Physician       Date:  2013-09-01       Impact factor: 3.292

Review 4.  Epidemiology of peripheral artery disease.

Authors:  Michael H Criqui; Victor Aboyans
Journal:  Circ Res       Date:  2015-04-24       Impact factor: 17.367

Review 5.  Epidemiology of limb loss and congenital limb deficiency: a review of the literature.

Authors:  Patti L Ephraim; Timothy R Dillingham; Mathilde Sector; Liliana E Pezzin; Ellen J Mackenzie
Journal:  Arch Phys Med Rehabil       Date:  2003-05       Impact factor: 3.966

6.  Disorders of carbohydrate and lipid metabolism in veterans with paraplegia or quadriplegia: a model of premature aging.

Authors:  W A Bauman; A M Spungen
Journal:  Metabolism       Date:  1994-06       Impact factor: 8.694

7.  Prevalence of and risk factors for peripheral arterial disease in the United States: results from the National Health and Nutrition Examination Survey, 1999-2000.

Authors:  Elizabeth Selvin; Thomas P Erlinger
Journal:  Circulation       Date:  2004-07-19       Impact factor: 29.690

8.  Pulse wave velocity for assessment of arterial stiffness among people with spinal cord injury: a pilot study.

Authors:  Masae Miyatani; Kei Masani; Paul I Oh; Motohiko Miyachi; Milos R Popovic; B Cathy Craven
Journal:  J Spinal Cord Med       Date:  2009       Impact factor: 1.985

9.  The morbidity and mortality following a diagnosis of peripheral arterial disease: long-term follow-up of a large database.

Authors:  Jaime Caro; Kristen Migliaccio-Walle; Khajak J Ishak; Irina Proskorovsky
Journal:  BMC Cardiovasc Disord       Date:  2005-06-22       Impact factor: 2.298

10.  A Systematic Review of the Incidence, Prevalence, Costs, and Activity and Work Limitations of Amputation, Osteoarthritis, Rheumatoid Arthritis, Back Pain, Multiple Sclerosis, Spinal Cord Injury, Stroke, and Traumatic Brain Injury in the United States: A 2019 Update.

Authors:  Jessica Lo; Leighton Chan; Spencer Flynn
Journal:  Arch Phys Med Rehabil       Date:  2020-04-24       Impact factor: 3.966

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