Literature DB >> 35754581

A concerning trend in geriatric pharmacy that merits evidence-based intervention.

Hunter Merritt Hughes1, Hamasah Nizami2, Juan Sebastian Polanco3, Jessica Poulson1, Alice Cai1, Rea Mittal1, Lilly Su1, Pranjal Jain4, Rohit Jain5.   

Abstract

The effects of polypharmacy on geriatric populations are an emerging concern that merits more exploration. The primary goal of this review was to evaluate the current body of knowledge on polypharmacy and explore the preventive and corrective measures to avoid negative outcomes. Even if a medication has an appropriate indication, polypharmacy in the geriatric population is associated with an increased risk of drug-drug or drug-condition interactions. Recent efforts to prevent polypharmacy include the development of interprofessional teams in clinics dedicated to medication review and reconciliation, deprescription plans aimed to safely discontinue potentially inappropriate medications, and inpatient screening tools that provide prescribing recommendations. In conclusion, polypharmacy affects a high percentage of the geriatric population. Current efforts to address and prevent polypharmacy are ongoing but have not been widely adopted.
Copyright © 2022 Baylor University Medical Center.

Entities:  

Keywords:  Cascade; geriatric; medication; polypharmacy; prescription; reconciliation

Year:  2022        PMID: 35754581      PMCID: PMC9196665          DOI: 10.1080/08998280.2022.2074211

Source DB:  PubMed          Journal:  Proc (Bayl Univ Med Cent)        ISSN: 0899-8280


  25 in total

1.  Medication overuse and misuse.

Authors:  Barbara J Zarowitz
Journal:  Geriatr Nurs       Date:  2006 Jul-Aug       Impact factor: 2.361

2.  Polypharmacy and falls in the middle age and elderly population.

Authors:  G Ziere; J P Dieleman; A Hofman; H A P Pols; T J M van der Cammen; B H Ch Stricker
Journal:  Br J Clin Pharmacol       Date:  2006-02       Impact factor: 4.335

3.  Reduction of potentially inappropriate medications using the STOPP criteria in frail older inpatients: a randomised controlled study.

Authors:  O Dalleur; B Boland; C Losseau; S Henrard; D Wouters; N Speybroeck; J M Degryse; A Spinewine
Journal:  Drugs Aging       Date:  2014-04       Impact factor: 3.923

4.  Deprescribing Unnecessary Medications: A Four-Part Process.

Authors:  Scott Endsley
Journal:  Fam Pract Manag       Date:  2018 May/Jun

5.  Adverse drug events in the outpatient setting: an 11-year national analysis.

Authors:  Florence T Bourgeois; Michael W Shannon; Clarissa Valim; Kenneth D Mandl
Journal:  Pharmacoepidemiol Drug Saf       Date:  2010-09       Impact factor: 2.890

6.  Prevalence of unplanned hospitalizations caused by adverse drug reactions in older veterans.

Authors:  Zachary A Marcum; Megan E Amuan; Joseph T Hanlon; Sherrie L Aspinall; Steven M Handler; Christine M Ruby; Mary Jo V Pugh
Journal:  J Am Geriatr Soc       Date:  2011-12-08       Impact factor: 5.562

7.  Is Polypharmacy Associated with Frailty in Older People? Results From the ESTHER Cohort Study.

Authors:  Kai-Uwe Saum; Ben Schöttker; Andreas D Meid; Bernd Holleczek; Walter E Haefeli; Klaus Hauer; Hermann Brenner
Journal:  J Am Geriatr Soc       Date:  2016-12-26       Impact factor: 5.562

8.  Prevalence and risk of potential cytochrome P450-mediated drug-drug interactions in older hospitalized patients with polypharmacy.

Authors:  Julie Doan; Hubert Zakrzewski-Jakubiak; Julie Roy; Jacques Turgeon; Cara Tannenbaum
Journal:  Ann Pharmacother       Date:  2013-03-12       Impact factor: 3.154

9.  Effects of polypharmacy on adverse drug reactions among geriatric outpatients at a tertiary care hospital in Karachi: a prospective cohort study.

Authors:  Bilal Ahmed; Kashmira Nanji; Rakshinda Mujeeb; Muhammad Junaid Patel
Journal:  PLoS One       Date:  2014-11-17       Impact factor: 3.240

10.  Teaching physicians the GPGP method promotes deprescribing in both inpatient and outpatient settings.

Authors:  Aaron Jason Bilek; Yuval Levy; Haneen Kab; Pavel Andreev; Doron Garfinkel
Journal:  Ther Adv Drug Saf       Date:  2019-12-27
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.