Literature DB >> 35747488

Study of patients with iron deficiency and HF in Ireland: prevalence and treatment budget impact.

Bethany Wong1, Sandra Redmond2, Ciara Blaine3, Carol-Ann Nugent3, Lavanya Saiva4, John Buckley5, Jim O'Neill6.   

Abstract

This study aims to present the screening, prevalence and treatment of heart failure (HF) patients with iron deficiency in an Irish hospital and use an economic model to estimate the budget impact of treating eligible patients with intravenous ferric carboxymaltose (IV FCM). Retrospective data were collected on 151 HF patients over a one-year period from all newly referred HF patients to a secondary care hospital. This included 36 patients with preserved ejection fraction (HFpEF) and 115 with reduced ejection fraction (HPrEF). An existing budget impact model was adapted to incorporate Irish unit cost and resource use data to estimate the annual budget impact of treating patients with IV FCM. The total number of HFrEF patients who met criteria for iron replacement was 44 (38% of total HFrEF patients); of this, only nine (20%) were treated. The budget impact model estimates that treating all eligible patients with IV FCM in this single centre would save 40 bed-days and over €7,600/year. To improve the quality of life and reduce hospitalisation, further identification and treatment of iron deficient patients should be implemented. Expanding the use of IV iron nationally would be cost and bed saving.
Copyright © 2021 Medinews (Cardiology) Limited.

Entities:  

Keywords:  Ireland; budget impact; heart failure; iron deficiency

Year:  2021        PMID: 35747488      PMCID: PMC8822530          DOI: 10.5837/bjc.2021.010

Source DB:  PubMed          Journal:  Br J Cardiol        ISSN: 0969-6113


  23 in total

1.  Heart failure with anemia: novel findings on the roles of renal disease, interleukins, and specific left ventricular remodeling processes.

Authors:  Eileen O'Meara; Jean L Rouleau; Michel White; Karine Roy; Lucie Blondeau; Anique Ducharme; Paul-Eduard Neagoe; Martin G Sirois; Joël Lavoie; Normand Racine; Mark Liszkowski; François Madore; Jean-Claude Tardif; Simon de Denus
Journal:  Circ Heart Fail       Date:  2014-07-15       Impact factor: 8.790

2.  Rehospitalization for heart failure: predict or prevent?

Authors:  Akshay S Desai; Lynne W Stevenson
Journal:  Circulation       Date:  2012-07-24       Impact factor: 29.690

3.  Prevalence of unrecognized heart failure in older persons with shortness of breath on exertion.

Authors:  Evelien E S van Riet; Arno W Hoes; Alexander Limburg; Marcel A J Landman; Henk van der Hoeven; Frans H Rutten
Journal:  Eur J Heart Fail       Date:  2014-05-26       Impact factor: 15.534

4.  Iron deficiency defined as depleted iron stores accompanied by unmet cellular iron requirements identifies patients at the highest risk of death after an episode of acute heart failure.

Authors:  Ewa A Jankowska; Monika Kasztura; Mateusz Sokolski; Marek Bronisz; Sylwia Nawrocka; Weronika Oleśkowska-Florek; Robert Zymliński; Jan Biegus; Paweł Siwołowski; Waldemar Banasiak; Stefan D Anker; Gerasimos Filippatos; John G F Cleland; Piotr Ponikowski
Journal:  Eur Heart J       Date:  2014-06-13       Impact factor: 29.983

5.  Improving evidence-based care for heart failure in outpatient cardiology practices: primary results of the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF).

Authors:  Gregg C Fonarow; Nancy M Albert; Anne B Curtis; Wendy Gattis Stough; Mihai Gheorghiade; J Thomas Heywood; Mark L McBride; Patches Johnson Inge; Mandeep R Mehra; Christopher M O'Connor; Dwight Reynolds; Mary Norine Walsh; Clyde W Yancy
Journal:  Circulation       Date:  2010-07-26       Impact factor: 29.690

6.  Ferric carboxymaltose in patients with heart failure and iron deficiency.

Authors:  Stefan D Anker; Josep Comin Colet; Gerasimos Filippatos; Ronnie Willenheimer; Kenneth Dickstein; Helmut Drexler; Thomas F Lüscher; Boris Bart; Waldemar Banasiak; Joanna Niegowska; Bridget-Anne Kirwan; Claudio Mori; Barbara von Eisenhart Rothe; Stuart J Pocock; Philip A Poole-Wilson; Piotr Ponikowski
Journal:  N Engl J Med       Date:  2009-11-17       Impact factor: 91.245

7.  Intravenous Iron in Patients Undergoing Maintenance Hemodialysis.

Authors:  Iain C Macdougall; Claire White; Stefan D Anker; Sunil Bhandari; Kenneth Farrington; Philip A Kalra; John J V McMurray; Heather Murray; Charles R V Tomson; David C Wheeler; Christopher G Winearls; Ian Ford
Journal:  N Engl J Med       Date:  2018-10-26       Impact factor: 91.245

Review 8.  Risk factors for anticoagulation-related bleeding complications in patients with atrial fibrillation: a systematic review.

Authors:  M Hughes; G Y H Lip
Journal:  QJM       Date:  2007-09-10

9.  2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC.

Authors:  Piotr Ponikowski; Adriaan A Voors; Stefan D Anker; Héctor Bueno; John G F Cleland; Andrew J S Coats; Volkmar Falk; José Ramón González-Juanatey; Veli-Pekka Harjola; Ewa A Jankowska; Mariell Jessup; Cecilia Linde; Petros Nihoyannopoulos; John T Parissis; Burkert Pieske; Jillian P Riley; Giuseppe M C Rosano; Luis M Ruilope; Frank Ruschitzka; Frans H Rutten; Peter van der Meer
Journal:  Eur Heart J       Date:  2016-05-20       Impact factor: 29.983

10.  Economic Evaluation of Ferric Carboxymaltose for the Management of Hemodialysis Patients with Iron Deficiency Anemia in Italy.

Authors:  Carla Rognoni; Vittorio Ortalda; Caterina Biasi; Giovanni Gambaro
Journal:  Adv Ther       Date:  2019-09-05       Impact factor: 3.845

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