| Literature DB >> 3573777 |
T Thomas, C Lorino, J J Ferrara.
Abstract
Fibromatosis is an uncommon, relatively benign though locally infiltrating neoplasm consisting of well-differentiated fibroblasts surrounded by collagen bundles. The majority of the literature suggests that prevention of local recurrence mandates wide (en bloc) excision. Few more than a dozen cases of primary breast fibromatosis have been reported. Herein the clinical characteristics, diagnostic evaluation, and therapeutic options are presented. Management should be based upon principles utilized for extra-mammary primary disease-en bloc resection. This may require total mastectomy and removal of pectoralis major muscle. Breast reconstruction should be deferred for a minimum of 3 years, during which time the majority of recurrences will have become manifest.Entities:
Mesh:
Year: 1987 PMID: 3573777 DOI: 10.1002/jso.2930350117
Source DB: PubMed Journal: J Surg Oncol ISSN: 0022-4790 Impact factor: 3.454