Literature DB >> 35737164

Pro-Gastrin-Releasing Peptide as a Marker of Small Cell Lung Cancer.

N V Lyubimova1, A E Kuz'minov1, A A Markovich1, A V Lebedeva1, Yu S Timofeev1, I S Stilidi1, N E Kushlinskii2.   

Abstract

The serum levels of pro-gastrin-releasing peptide (proGRP), neuron-specific enolase (NSE), and chromogranin A (CgA) were studied in 69 patients with small cell lung cancer and 50 apparently healthy donors. A significant increase of all studied biochemical markers was revealed in small cell lung cancer patients, while the highest diagnostic efficiency was demonstrated by proGRP compared to NSE and CgA. ProGRP is a promising biochemical marker of small cell lung cancer, especially sensitive in patients with distant metastases (in the brain, liver, and bones).
© 2022. Springer Science+Business Media, LLC, part of Springer Nature.

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Keywords:  blood serum; chromogranin A; neuron-specific enolase; pro-gastrin-releasing peptide; small cell lung cancer

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Year:  2022        PMID： 35737164     DOI： 10.1007/s10517-022-05529-9

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  12 in total

1.  Gastroenteropancreatic neuroendocrine neoplasms: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Authors:  M Pavel; K Öberg; M Falconi; E P Krenning; A Sundin; A Perren; A Berruti
Journal:  Ann Oncol       Date:  2020-04-06       Impact factor: 32.976

2.  Diagnostic value of ProGRP for small cell lung cancer in different stages.

Authors:  Aoran Dong; Jiali Zhang; Xiaobin Chen; Xiubao Ren; Xinwei Zhang
Journal:  J Thorac Dis       Date:  2019-04       Impact factor: 2.895

3.  Targeted determination of the early stage SCLC specific biomarker pro-gastrin-releasing peptide (ProGRP) at clinical concentration levels in human serum using LC-MS.

Authors:  Bjørn Winther; Petter Moi; Elisabeth Paus; J Léon E Reubsaet
Journal:  J Sep Sci       Date:  2007-11       Impact factor: 3.645

4.  Production and Characterization of Monoclonal Antibodies for Immunoassay of the Lung Cancer Marker proGRP.

Authors:  Marianne S Nordlund; Christian Fermer; Olle Nilsson; David J Warren; Elisabeth Paus
Journal:  Tumour Biol       Date:  2007-02-07

5.  Usefulness of serum tumor markers, including progastrin-releasing peptide, in patients with lung cancer: correlation with histology.

Authors:  Rafael Molina; Josep M Augé; Xavier Bosch; José M Escudero; Nuria Viñolas; Ramón Marrades; José Ramírez; Enric Carcereny; Xavier Filella
Journal:  Tumour Biol       Date:  2009-06-09

Review 6.  Biochemical Testing in Neuroendocrine Tumors.

Authors:  Vidya Aluri; Joseph S Dillon
Journal:  Endocrinol Metab Clin North Am       Date:  2017-06-12       Impact factor: 4.741

7.  The prognostic significance of the circulating neuroendocrine markers chromogranin A, pro-gastrin-releasing peptide, and neuron-specific enolase in patients with small-cell lung cancer.

Authors:  Marina Petrović; Zoran Bukumirić; Vladimir Zdravković; Slobodanka Mitrović; Henry Dushan Atkinson; Vladimir Jurišić
Journal:  Med Oncol       Date:  2013-12-30       Impact factor: 3.064

8.  Meta-Analysis of Serum Gastrin-Releasing Peptide Precursor as a Biomarker for Diagnosis of Small Cell Lung Cancer

Authors:  Shui Ping Lv; Yi Wang; Lang Huang; Fei Wang; Jian Guo Zhou; Hu Ma
Journal:  Asian Pac J Cancer Prev       Date:  2017-02-01

9.  Clinical significance of progastrin-releasing peptide, neuron-specific enolase, chromogranin a, and squamous cell cancer antigen in pulmonary neuroendocrine tumors

Authors:  Nuri Tutar; Nur Aleyna Yetkin; Cevat Yazıcı; Ömer Önal; Olgun Kontaş; Fahrettin Keleştemur
Journal:  Turk J Med Sci       Date:  2019-06-18       Impact factor: 0.973

10.  Evaluation of chemiluminescent immunoassay quantitative detection for pro-gastrin-releasing peptide (ProGRP) in serum and plasma.

Authors:  Yizhuang Cheng; Jing He; Liping Zhang; Xiufa Chen; Saiying Ou
Journal:  J Int Med Res       Date:  2019-12-19       Impact factor: 1.671
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