| Literature DB >> 357355 |
H Craane, J J Emeis, J Lindeman, W Nieuwenhuizen.
Abstract
In tissue of rats with disseminated intravascular coagulation, fibrin microthrombi can be sensitively detected by immunohistochemical methods, using antisera against rat fibrinogen or fibrin monomer. An indirect immunoperoxidase procedure on paraplast-embedded sections yields best results with regard to the morphology of the thrombi and their localization in the tissue. Only fibrillar immunoreactive material, oriented lengthwise in the vessels, should be regarded as microthrombi formed in vivo.Entities:
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Year: 1978 PMID: 357355 DOI: 10.1007/bf00496674
Source DB: PubMed Journal: Histochemistry ISSN: 0301-5564