Suwen Wu1, Chune Gan1, Xiaoling Huang1, Dongping Jiang2, Ye Xu3, Yixia Liao4, Fen Ma1, Yutong Hong1, Hao Duan5, Peng Lin1. 1. Department of Thoracic Surgery, Sun Yat-sen University Cancer Centre; State Key Laboratory of Oncology in South China; Collaborative Innovation Centre for Cancer Medicine; Guangzhou, China. 2. Department of Radiology, Sun Yat-sen University Cancer Centre; State Key Laboratory of Oncology in South China; Collaborative Innovation Centre for Cancer Medicine; Guangzhou, China. 3. Department of Anaesthesia, Sun Yat-sen University Cancer Centre; State Key Laboratory of Oncology in South China; Collaborative Innovation Centre for Cancer Medicine; Guangzhou, China. 4. The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China. 5. Department of Neurosurgery/Neuro-oncology, Sun Yat-sen University Cancer Centre; State Key Laboratory of Oncology in South China; Collaborative Innovation Centre for Cancer Medicine; Guangzhou, China.
Abstract
OBJECTIVE: To investigate the occurrence rate and risk factors of postoperative nausea and vomiting (PONV) in lung cancer patients following lobectomy and application of analgesic pumps. METHODS: This retrospective study reviewed clinical data from patients that had undergone lobectomy for lung cancer under general anaesthesia. The risk factors of PONV were analysed using binary logistic regression models. RESULTS: A total of 203 patients (97 females) were enrolled. The rate of PONV was 29.6% (60 of 203 patients) for all patients, 42.3% (41 of 97 patients) for female patients and 17.9% (19 of 106 patients) for male patients. Female patients undergoing thoracotomy (odds ratio [OR] 7.770, 95% confidence interval [CI] 1.747, 34.568) or having surgery durations ≥120 min (OR 4.493, 95% CI 1.502, 12.851) were significantly more susceptible to PONV. The risk of PONV in female patients that received postoperative dolasetron (100 mg, once a day) was significantly lower (OR 0.075, 95% CI 0.007, 0.834). For male patients, the risk of PONV was significantly lower in those with a body mass index ≥24 kg/m2 (OR 0.166; 95% CI 0.035, 0.782). CONCLUSION: Female and male patients have different risk factors for PONV following lobectomy for lung cancer and application of analgesic pumps.
OBJECTIVE: To investigate the occurrence rate and risk factors of postoperative nausea and vomiting (PONV) in lung cancer patients following lobectomy and application of analgesic pumps. METHODS: This retrospective study reviewed clinical data from patients that had undergone lobectomy for lung cancer under general anaesthesia. The risk factors of PONV were analysed using binary logistic regression models. RESULTS: A total of 203 patients (97 females) were enrolled. The rate of PONV was 29.6% (60 of 203 patients) for all patients, 42.3% (41 of 97 patients) for female patients and 17.9% (19 of 106 patients) for male patients. Female patients undergoing thoracotomy (odds ratio [OR] 7.770, 95% confidence interval [CI] 1.747, 34.568) or having surgery durations ≥120 min (OR 4.493, 95% CI 1.502, 12.851) were significantly more susceptible to PONV. The risk of PONV in female patients that received postoperative dolasetron (100 mg, once a day) was significantly lower (OR 0.075, 95% CI 0.007, 0.834). For male patients, the risk of PONV was significantly lower in those with a body mass index ≥24 kg/m2 (OR 0.166; 95% CI 0.035, 0.782). CONCLUSION: Female and male patients have different risk factors for PONV following lobectomy for lung cancer and application of analgesic pumps.
Entities:
Keywords:
Lung cancer; analgesic pumps; lobectomy; postoperative nausea and vomiting
Authors: B K Philip; M H Pearman; A L Kovac; J E Chelly; B V Wetchler; R McKenzie; T G Monk; M Dershwitz; M Mingus; Y F Sung; W F Hahne; R A Brown Journal: Eur J Anaesthesiol Date: 2000-01 Impact factor: 4.330
Authors: Tong J Gan; Kumar G Belani; Sergio Bergese; Frances Chung; Pierre Diemunsch; Ashraf S Habib; Zhaosheng Jin; Anthony L Kovac; Tricia A Meyer; Richard D Urman; Christian C Apfel; Sabry Ayad; Linda Beagley; Keith Candiotti; Marina Englesakis; Traci L Hedrick; Peter Kranke; Samuel Lee; Daniel Lipman; Harold S Minkowitz; John Morton; Beverly K Philip Journal: Anesth Analg Date: 2020-08 Impact factor: 5.108