| Literature DB >> 35734360 |
Shivani Gupta1, Manisha Jhirwal1, Charu Sharma1, Shashank Shekhar1.
Abstract
Choriocarcinoma is a rare highly malignant neoplasm which may present with early metastases as it has a propensity of rapid haematogenous spread. However the neoplasm is chemosensitive and has a good prognosis even in advanced stages. We are presenting a case of a 26 years old female with early pregnancy presented with lung and vaginal metastases with obstructive jaundice. [International Federation of Gynaecology and Obstetrics (FIGO) stage III; World Health Organization score, 14]. Serum beta-hCG was 3,61,131 mIU/ml. Radiological evaluation suggested marked lung metastases with vaginal metastases. Patient was started on single agent chemotherapy doxorubicin in view of deranged liver function test. Patient was given 5 cycles of doxorubicin with liver function test and beta hcg monitoring. After liver function test normalized, patient was shifted to EMACO regimen for 6 cycles of treatment dose and 2 cycles of maintenance dose. © Federation of Obstetric & Gynecological Societies of India 2021.Entities:
Keywords: Beta hCG; Chemotherapy; Doxorubicin; EMACO; Molar pregnancy
Year: 2021 PMID: 35734360 PMCID: PMC9206957 DOI: 10.1007/s13224-021-01490-1
Source DB: PubMed Journal: J Obstet Gynaecol India ISSN: 0975-6434