| Literature DB >> 35734215 |
Alejandro J Martinez Herrada1, Michael A Wien2, Steven L Shein1, John K Maher3, Janine E Zee-Cheng4, Alexandre T Rotta5.
Abstract
We developed a novel airway clearance and lung recruitment maneuver for children with refractory unilateral atelectasis undergoing invasive mechanical ventilation. In this retrospective, single-center, proof of concept study, we describe the steps involved in this novel maneuver and evaluate its effectiveness in 15 patients through objective quantitation of changes in respiratory system compliance and in the degree of atelectasis assessed by a validated Modified Radiology Atelectasis Score. Compared with the premaneuver baseline, the median atelectasis score improved significantly following the maneuver (9 [7.5-10] vs. 1 [0-3.3], respectively, p < 0.01). Likewise, dynamic compliance was significantly higher following the maneuver (0.3 [0.32-0.44] vs. 0.61 [0.53-0.69] mL/kg/cm H 2 O, respectively, p < 0.01). No patients required a bronchoscopy. This simple and effective maneuver resulted in a significant improvement in the degree of atelectasis and dynamic compliance in this cohort of mechanically ventilated children with refractory unilateral atelectasis. Thieme. All rights reserved.Entities:
Keywords: atelectasis; mechanical ventilation; pediatric critical care
Year: 2020 PMID: 35734215 PMCID: PMC9208838 DOI: 10.1055/s-0040-1721508
Source DB: PubMed Journal: J Pediatr Intensive Care ISSN: 2146-4626