Literature DB >> 35734215

A Novel Maneuver to Treat Refractory Atelectasis in Mechanically Ventilated Children.

Alejandro J Martinez Herrada1, Michael A Wien2, Steven L Shein1, John K Maher3, Janine E Zee-Cheng4, Alexandre T Rotta5.   

Abstract

We developed a novel airway clearance and lung recruitment maneuver for children with refractory unilateral atelectasis undergoing invasive mechanical ventilation. In this retrospective, single-center, proof of concept study, we describe the steps involved in this novel maneuver and evaluate its effectiveness in 15 patients through objective quantitation of changes in respiratory system compliance and in the degree of atelectasis assessed by a validated Modified Radiology Atelectasis Score. Compared with the premaneuver baseline, the median atelectasis score improved significantly following the maneuver (9 [7.5-10] vs. 1 [0-3.3], respectively, p  < 0.01). Likewise, dynamic compliance was significantly higher following the maneuver (0.3 [0.32-0.44] vs. 0.61 [0.53-0.69] mL/kg/cm H 2 O, respectively, p  < 0.01). No patients required a bronchoscopy. This simple and effective maneuver resulted in a significant improvement in the degree of atelectasis and dynamic compliance in this cohort of mechanically ventilated children with refractory unilateral atelectasis. Thieme. All rights reserved.

Entities:  

Keywords:  atelectasis; mechanical ventilation; pediatric critical care

Year:  2020        PMID: 35734215      PMCID: PMC9208838          DOI: 10.1055/s-0040-1721508

Source DB:  PubMed          Journal:  J Pediatr Intensive Care        ISSN: 2146-4626


  26 in total

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9.  Recombinant human deoxyribonuclease improves atelectasis in mechanically ventilated children with cardiac disease.

Authors:  Parthak Prodhan; B Greenberg; Adnan T Bhutta; Carrie Hyde; Ajay Vankatesan; Michiaki Imamura; Robert Db Jaquiss; Umesh Dyamenahalli
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  1 in total

1.  Refractory Atelectasis and Response to Chest Physiotherapy.

Authors:  Simon Gates; Ellie Melkuhn; Brenda Morrow; George Ntoumenopoulos; Harriet Shannon; Emma Shkurka
Journal:  J Pediatr Intensive Care       Date:  2021-06-01
  1 in total

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