G Teferra1, K Teklemariam2, D F Wares3, C Negeri4, A Bedru1. 1. KNCV Tuberculosis Foundation, Addis Ababa, Ethiopia. 2. Organic Health Care Service, Addis Ababa, Ethiopia. 3. KNCV Tuberculosis Foundation, The Hague, The Netherlands. 4. United Nations Development Programme, Juba, South Sudan.
Abstract
SETTING: Previous and current patients with drug-resistant TB (DR-TB) who had documented treatment-related hearing impairment due to second-line injectable (SLI) use were identified from different DR-TB treatment initiation centres in Ethiopia. OBJECTIVE: To assess selected patients with DR-TB for eligibility for hearing aids and provide hearing aids to 10 eligible patients. DESIGN: This was an observational cohort study. Patients were followed up for 8 months, with hearing assessments conducted at 1, 3 and 8 months to objectively assess hearing capacity. RESULTS: Of 12 patients assessed for hearing aids eligibility, 10 were fitted with hearing aids (type XTM XP P4) and followed up for 8 months. "Formal" improvement was observed only in one patient. However, "general quality of life" appeared to be improved in nine patients. CONCLUSION: Minimal "formal" improvement was observed. However, the study was too small to say whether hearing aids should, or should not, be recommended as a public health measure. This needs a larger better controlled follow-up study. The all-oral DR-TB treatment regimens should be used for all patients with DR-TB in Ethiopia. However, as a proportion of patients with DR-TB are likely to continue receiving SLIs in the foreseeable future, they will require close audiometry assessment and appropriate care.
SETTING: Previous and current patients with drug-resistant TB (DR-TB) who had documented treatment-related hearing impairment due to second-line injectable (SLI) use were identified from different DR-TB treatment initiation centres in Ethiopia. OBJECTIVE: To assess selected patients with DR-TB for eligibility for hearing aids and provide hearing aids to 10 eligible patients. DESIGN: This was an observational cohort study. Patients were followed up for 8 months, with hearing assessments conducted at 1, 3 and 8 months to objectively assess hearing capacity. RESULTS: Of 12 patients assessed for hearing aids eligibility, 10 were fitted with hearing aids (type XTM XP P4) and followed up for 8 months. "Formal" improvement was observed only in one patient. However, "general quality of life" appeared to be improved in nine patients. CONCLUSION: Minimal "formal" improvement was observed. However, the study was too small to say whether hearing aids should, or should not, be recommended as a public health measure. This needs a larger better controlled follow-up study. The all-oral DR-TB treatment regimens should be used for all patients with DR-TB in Ethiopia. However, as a proportion of patients with DR-TB are likely to continue receiving SLIs in the foreseeable future, they will require close audiometry assessment and appropriate care.
Authors: James A Seddon; Peter Godfrey-Faussett; Kayleen Jacobs; Adam Ebrahim; Anneke C Hesseling; H Simon Schaaf Journal: Eur Respir J Date: 2012-06-14 Impact factor: 16.671
Authors: A Reuter; P Tisile; D von Delft; H Cox; V Cox; L Ditiu; A Garcia-Prats; S Koenig; E Lessem; R Nathavitharana; J A Seddon; J Stillo; A von Delft; J Furin Journal: Int J Tuberc Lung Dis Date: 2017-11-01 Impact factor: 2.373