| Literature DB >> 3573047 |
Abstract
Free radical generation may be the principal pathogenic factor responsible for the initiation of ischemia/reperfusion myocardial cell damage. Circumstantial evidence is in favour of the view that impaired function of the membraneous components of ischemic cells is associated with oxygen radical-induced alterations in proteins and lipids. Thus, lipid antioxidants and free radical scavengers as well as antagonists of protein modification may all be required for therapeutic intervention of this aspect of ischemia/reperfusion injury.Entities:
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Year: 1987 PMID： 3573047 DOI： 10.1016/s0022-2828(87)80563-1
Source DB: PubMed Journal: J Mol Cell Cardiol ISSN： 0022-2828 Impact factor: 5.000