F J Ahlhelm1, A A Tarnutzer2, K Shariat3. 1. Abteilung Neuroradiologie, Zentrum für Bildgebung, Kantonsspital Baden AG, Im Ergel 1, 5404, Baden, Schweiz. frankjohannes.ahlhelm@ksb.ch. 2. Neurologie, Kantonsspital Baden AG, Baden, Schweiz. 3. Klinik für Neurochirurgie, Kantonsspital Winterthur, Winterthur, Schweiz.
Abstract
CLINICAL/METHODICAL ISSUE: Cavernous malformations or cavernomas belong to the angiodysplasias. They may be sporadic or familial and cause symptoms (epilepsy) despite the absence of a left-to-right shunt. In addition to intracranial locations, spinal cavernomas are also found. STANDARD RADIOLOGICAL METHODS: Magnetic resonance imaging (MRI) and computed tomography (CT) are used for diagnosis PERFORMANCE: MRI, except for acutely or subacutely hemorrhaged cavernomas, is superior to CT for lesion detection. ACHIEVEMENTS: CT is reserved for acute diagnosis. MRI, especially susceptibility-sensitive gradient echo sequences, can also detect cavernomas without (sub-)acute hemorrhage or calcifications. PRACTICAL RECOMMENDATIONS: MRI is also useful for differentiating the familial form vs. sporadic form. Digital subtraction angiography (DSA) is used for differential diagnosis in rare cases, as cavernomas show no correlate here.
CLINICAL/METHODICAL ISSUE: Cavernous malformations or cavernomas belong to the angiodysplasias. They may be sporadic or familial and cause symptoms (epilepsy) despite the absence of a left-to-right shunt. In addition to intracranial locations, spinal cavernomas are also found. STANDARD RADIOLOGICAL METHODS: Magnetic resonance imaging (MRI) and computed tomography (CT) are used for diagnosis PERFORMANCE: MRI, except for acutely or subacutely hemorrhaged cavernomas, is superior to CT for lesion detection. ACHIEVEMENTS: CT is reserved for acute diagnosis. MRI, especially susceptibility-sensitive gradient echo sequences, can also detect cavernomas without (sub-)acute hemorrhage or calcifications. PRACTICAL RECOMMENDATIONS: MRI is also useful for differentiating the familial form vs. sporadic form. Digital subtraction angiography (DSA) is used for differential diagnosis in rare cases, as cavernomas show no correlate here.
Authors: M C Mabray; J Starcevich; J Hallstrom; M Robinson; M Bartlett; J Nelson; A Zafar; H Kim; L Morrison; B L Hart Journal: AJNR Am J Neuroradiol Date: 2020-05-28 Impact factor: 3.825
Authors: Felix Rosenow; Mario A Alonso-Vanegas; Christoph Baumgartner; Ingmar Blümcke; Maria Carreño; Elke R Gizewski; Hajo M Hamer; Susanne Knake; Philippe Kahane; Hans O Lüders; Gary W Mathern; Katja Menzler; Jonathan Miller; Taisuke Otsuki; Cigdem Ozkara; Asla Pitkänen; Steven N Roper; Americo C Sakamoto; Ulrich Sure; Matthew C Walker; Bernhard J Steinhoff Journal: Epilepsia Date: 2013-10-17 Impact factor: 5.864