Literature DB >> 35725138

Childhood Neighborhood Disadvantage, Parenting, and Adult Health.

Sylvie Mrug1, Malcolm Barker-Kamps2, Catheryn A Orihuela2, Amit Patki3, Hemant K Tiwari3.   

Abstract

INTRODUCTION: Growing up in disadvantaged neighborhoods is associated with poor adult health indicators. Consistent and supportive parenting plays a key role in life-long health, but it is not known whether positive parenting can mitigate the relationship between neighborhood adversity and poor health. This study examines parenting as a moderator of the links between childhood neighborhood characteristics and adult health indicators.
METHODS: A sample of 305 individuals (61% female; 82% African American, 18% Caucasian) were assessed in childhood (T1; age 11 years; 2003‒2004) and adulthood (T2; age 27 years; 2018‒2021). At T1, neighborhood poverty was derived from census data; neighborhood disorder was reported by parents. Children reported on parental harsh discipline, inconsistent discipline, and parental nurturance. At T2, health outcomes included BMI, serum cortisol and C-reactive protein (CRP), and salivary DNA methylation index related to CRP. Regression models predicted T2 health outcomes from T1 neighborhood and parenting variables and their interactions, adjusting for clustering and confounders. Data were analyzed in 2021.
RESULTS: Neighborhood poverty was associated with lower cortisol, whereas neighborhood disorder was linked with CRP‒related DNA methylation. Multiple interactions between neighborhood and parenting variables emerged, indicating that adverse neighborhood conditions were only related to poor adult health when combined with inconsistent discipline and low parental nurturance. By contrast, warm and supportive parenting, consistent discipline, and to a lesser extent harsh discipline buffered children from poor health outcomes associated with neighborhood disadvantage.
CONCLUSIONS: Interventions enhancing consistent and nurturing parenting may help to reduce the long-term associations of neighborhood disadvantage with poor health.
Copyright © 2022 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2022        PMID: 35725138      PMCID: PMC9219037          DOI: 10.1016/j.amepre.2022.01.028

Source DB:  PubMed          Journal:  Am J Prev Med        ISSN: 0749-3797            Impact factor:   6.604


  79 in total

1.  Childhood abuse, parental warmth, and adult multisystem biological risk in the Coronary Artery Risk Development in Young Adults study.

Authors:  Judith E Carroll; Tara L Gruenewald; Shelley E Taylor; Denise Janicki-Deverts; Karen A Matthews; Teresa E Seeman
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-23       Impact factor: 11.205

Review 2.  Allostatic load biomarkers of chronic stress and impact on health and cognition.

Authors:  Robert-Paul Juster; Bruce S McEwen; Sonia J Lupien
Journal:  Neurosci Biobehav Rev       Date:  2009-10-12       Impact factor: 8.989

3.  A state-trait model of cortisol in early childhood: Contextual and parental predictors of stable and time-varying effects.

Authors:  Stephanie F Thompson; Maureen Zalewski; Cara J Kiff; Liliana J Lengua
Journal:  Horm Behav       Date:  2018-02-09       Impact factor: 3.587

4.  Regression-based statistical mediation and moderation analysis in clinical research: Observations, recommendations, and implementation.

Authors:  Andrew F Hayes; Nicholas J Rockwood
Journal:  Behav Res Ther       Date:  2016-11-05

5.  Cumulative neighborhood risk of psychosocial stress and allostatic load in adolescents.

Authors:  Katherine P Theall; Stacy S Drury; Elizabeth A Shirtcliff
Journal:  Am J Epidemiol       Date:  2012-10-01       Impact factor: 4.897

Review 6.  The role of DNA methylation in the association between childhood adversity and cardiometabolic disease.

Authors:  Guang Hao; Nagy A Youssef; Catherine L Davis; Shaoyong Su
Journal:  Int J Cardiol       Date:  2017-12-24       Impact factor: 4.164

7.  The indelible weight of place: Childhood neighborhood disadvantage, timing of exposure, and obesity across adulthood.

Authors:  Steven Elías Alvarado
Journal:  Health Place       Date:  2019-07-04       Impact factor: 4.078

8.  Prenatal maternal stress and cord blood innate and adaptive cytokine responses in an inner-city cohort.

Authors:  Rosalind J Wright; Cynthia M Visness; Agustin Calatroni; Mitchell H Grayson; Diane R Gold; Megan T Sandel; Aviva Lee-Parritz; Robert A Wood; Meyer Kattan; Gordon R Bloomberg; Melissa Burger; Alkis Togias; Frank R Witter; Rhoda S Sperling; Yoel Sadovsky; James E Gern
Journal:  Am J Respir Crit Care Med       Date:  2010-03-01       Impact factor: 21.405

9.  Tobacco smoking leads to extensive genome-wide changes in DNA methylation.

Authors:  Sonja Zeilinger; Brigitte Kühnel; Norman Klopp; Hansjörg Baurecht; Anja Kleinschmidt; Christian Gieger; Stephan Weidinger; Eva Lattka; Jerzy Adamski; Annette Peters; Konstantin Strauch; Melanie Waldenberger; Thomas Illig
Journal:  PLoS One       Date:  2013-05-17       Impact factor: 3.240

10.  DNA methylation arrays as surrogate measures of cell mixture distribution.

Authors:  Eugene Andres Houseman; William P Accomando; Devin C Koestler; Brock C Christensen; Carmen J Marsit; Heather H Nelson; John K Wiencke; Karl T Kelsey
Journal:  BMC Bioinformatics       Date:  2012-05-08       Impact factor: 3.169

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.