| Literature DB >> 35717486 |
Jonathan Noël1, Subuhee Ahmed2, Anya Mascarenhas3, Daniel Stirt4, Marcio Moschovas5, Ela Patel5, Sunil Reddy5, Seetharam Bhat6, Travis Rogers5, Vipul Patel5.
Abstract
Post radical prostatectomy (RP) erectile dysfunction and incontinence impacts quality of life for patients. In an objective to hasten the recovery of these functional outcomes, human placental derived allografts laid on neurovascular bundles (NVB) have been investigated. These grafts include amniotic membranes (AM) chorionic membranes (CM) or umbilical cord (UC) allografts. A literature review performed using the MeSH terms "AMNION" OR "CHORION" OR "AMNIOTIC MEMBRANE" OR "UMBILICAL CORD" AND "PROSTATE CANCER" from no specified start date, to April 2022. 163 articles were retrieved, with 149 articles excluded. 14 articles were eligible and analysed. 5 articles were included in this review for an analysis on comparative outcomes. The average return to potency was statistically significant in the intervention groups. Positive surgical margin (PSM) rates showed a higher rate in the control groups. BCR was observed at a lower rate in the interventional group. This review reveals a benefit from human placental allograft's ability to hasten post RP functional recovery, without impacting oncological control.Entities:
Keywords: Allograft; Amniotic membrane; Biomaterials; Chorionic membrane; Outcomes; Prostate cancer; Prostatectomy; Robotics; Umbilical cord graft
Year: 2022 PMID： 35717486 DOI： 10.1007/s11701-022-01433-6
Source DB: PubMed Journal: J Robot Surg ISSN： 1863-2483