| Literature DB >> 35717208 |
Shuangjian Jiang1, Chengqiang Mo1, Shengjie Guo2, Jintao Zhuang3, Bin Huang1, Xiaopeng Mao4.
Abstract
Entities:
Year: 2022 PMID: 35717208 PMCID: PMC9206288 DOI: 10.1186/s13046-022-02417-y
Source DB: PubMed Journal: J Exp Clin Cancer Res ISSN: 0392-9078
Fig. 8hBMSCs-derived exosomal miR-205 inhibits LNCaP cell proliferation, invasion, and migration and enhances apoptosis. a proliferation of LNCaP cells treated with hBMSCs and miR-205 measured using EdU assay (× 200); b apoptosis of LNCaP cells treated with hBMSCs and miR-205 measured using flow cytometry; Abscissa represents apoptotic cells identified by Annexin V-FITC and ordinate represents dead cells identified by PI; c invasion and migration of LNCaP cells treated with hBMSCs and miR-205 measured using Transwell assay (× 200); d protein band patterns and levels of Ki67, PCNA, MMP-2, MMP-9, Bcl-2, and Bax measured in LNCaP cells treated with hBMSCs and miR-205 determined using western blot analysis; *, p < 0.05. Measurement data were expressed as mean ± standard deviation; comparisons between two groups were analyzed using unpaired t-test; the experiment was repeated 3 times independently