Literature DB >> 3571392

Assay of ambroxol in biological fluids by capillary gas-liquid chromatography.

J Schmid.   

Abstract

A sensitive and rapid method for the determination of ambroxol in biological fluids is described. It comprises a single extraction step, derivatization and selective determination with capillary gas-liquid chromatography (in split-mode) and electron-capture detection. The limit of quantification in plasma is ca. 3 ng/ml. The method is applied to the pharmacokinetics of ambroxol in humans.

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Year:  1987        PMID： 3571392     DOI： 10.1016/0378-4347(87)80025-7

Source DB:  PubMed          Journal:  J Chromatogr


  5 in total

1.  Ambroxol lozenge bioavailability : an open-label, two-way crossover study of the comparative bioavailability of ambroxol lozenges and commercial tablets in healthy thai volunteers.

Authors:  Malee Rojpibulstit; Srirat Kasiwong; Siwasak Juthong; Narubodee Phadoongsombat; Damrongsak Faroongsarng
Journal:  Clin Drug Investig       Date:  2003       Impact factor: 2.859

2.  RP-HPLC and Spectrophotometric Estimation of Ambroxol Hydrochloride and Cetirizine Hydrochloride in Combined Dosage Form.

Authors:  Neela M Bhatia; S K Ganbavale; M S Bhatia; H N More; S U Kokil
Journal:  Indian J Pharm Sci       Date:  2008-09       Impact factor: 0.975

3.  A Rapid, Stability Indicating RP-UPLC Method for Simultaneous Determination of Ambroxol Hydrochloride, Cetirizine Hydrochloride and Antimicrobial Preservatives in Liquid Pharmaceutical Formulation.

Authors:  Rakshit Kanubhai Trivedi; Mukesh C Patel; Sushant B Jadhav
Journal:  Sci Pharm       Date:  2011-05-26

4.  Isolation, Identification, and Characterization of One Degradation Product in Ambroxol by HPLC-Hyphenated Techniques.

Authors:  Veera Raghava Raju Thummala; Mrutyunjaya Rao Ivaturi; Someswara Rao Nittala
Journal:  Sci Pharm       Date:  2014-01-12

5.  Simultaneous UV Spectrophotometric Estimation of Ambroxol Hydrochloride and Levocetirizine Dihydrochloride.

Authors:  S Lakshmana Prabhu; A A Shirwaikar; Annie Shirwaikar; C Dinesh Kumar; G Aravind Kumar
Journal:  Indian J Pharm Sci       Date:  2008 Mar-Apr       Impact factor: 0.975
  5 in total

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