Literature DB >> 3570980

Mulundocandin, a new lipopeptide antibiotic. II. Structure elucidation.

T Mukhopadhyay, B N Ganguli, H W Fehlhaber, H Kogler, L Vertesy.   

Abstract

The structure of a new antifungal antibiotic, mulundocandin, C48H77N7O16, was elucidated by high field NMR experiments e.g., homo- and heteronuclear correlation spectra, distortionless enhancement by polarization transfer (DEPT) spectra as well as nuclear Overhauser effect. The compound is a lipopeptide antibiotic belonging to the echinocandin class.

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Year:  1987        PMID： 3570980     DOI： 10.7164/antibiotics.40.281

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  11 in total

1.  Discovery of novel antifungal (1,3)-beta-D-glucan synthase inhibitors.

Authors:  J Onishi; M Meinz; J Thompson; J Curotto; S Dreikorn; M Rosenbach; C Douglas; G Abruzzo; A Flattery; L Kong; A Cabello; F Vicente; F Pelaez; M T Diez; I Martin; G Bills; R Giacobbe; A Dombrowski; R Schwartz; S Morris; G Harris; A Tsipouras; K Wilson; M B Kurtz
Journal:  Antimicrob Agents Chemother       Date:  2000-02       Impact factor: 5.191

Review 2.  Antifungal peptides: novel therapeutic compounds against emerging pathogens.

Authors:  A J De Lucca; T J Walsh
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

3.  Aspergillus mulundensis sp. nov., a new species for the fungus producing the antifungal echinocandin lipopeptides, mulundocandins.

Authors:  Gerald F Bills; Qun Yue; Li Chen; Yan Li; Zhiqiang An; Jens C Frisvad
Journal:  J Antibiot (Tokyo)       Date:  2015-10-14       Impact factor: 2.649

4.  Evolution of Chemical Diversity in Echinocandin Lipopeptide Antifungal Metabolites.

Authors:  Qun Yue; Li Chen; Xiaoling Zhang; Kuan Li; Jingzu Sun; Xingzhong Liu; Zhiqiang An; Gerald F Bills
Journal:  Eukaryot Cell       Date:  2015-05-29

5.  Utility of 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenyl-amino)carbonyl]-2H-tetrazolium hydroxide (XTT) and minimum effective concentration assays in the determination of antifungal susceptibility of Aspergillus fumigatus to the lipopeptide class compounds.

Authors:  S P Hawser; C Jessup; J Vitullo; M A Ghannoum
Journal:  J Clin Microbiol       Date:  2001-07       Impact factor: 5.948

6.  Aspergillus section Nidulantes (formerly Emericella): Polyphasic taxonomy, chemistry and biology.

Authors:  A J Chen; J C Frisvad; B D Sun; J Varga; S Kocsubé; J Dijksterhuis; D H Kim; S-B Hong; J Houbraken; R A Samson
Journal:  Stud Mycol       Date:  2016-10-19       Impact factor: 16.097

7.  Peptide-based Antifungal Therapies against Emerging Infections.

Authors:  A Matejuk; Q Leng; M D Begum; M C Woodle; P Scaria; S-T Chou; A J Mixson
Journal:  Drugs Future       Date:  2010-03       Impact factor: 0.148

8.  Apc.LaeA and Apc.VeA of the velvet complex govern secondary metabolism and morphological development in the echinocandin-producing fungus Aspergillus pachycristatus.

Authors:  Nan Lan; Qun Yue; Zhiqiang An; Gerald F Bills
Journal:  J Ind Microbiol Biotechnol       Date:  2019-11-23       Impact factor: 3.346

Review 9.  Structural Diversity and Biological Activities of Fungal Cyclic Peptides, Excluding Cyclodipeptides.

Authors:  Xiaohan Wang; Minyi Lin; Dan Xu; Daowan Lai; Ligang Zhou
Journal:  Molecules       Date:  2017-11-27       Impact factor: 4.411

10.  Functional redundancy in Echinocandin B in-cluster transcription factor ecdB of Emericella rugulosa NRRL 11440.

Authors:  Arvind Kumar; Varun Jaiswal; Vinay Kumar; Amitava Dey; Antresh Kumar
Journal:  Biotechnol Rep (Amst)       Date:  2018-06-09
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