| Literature DB >> 35707158 |
Zhe Gao1, Zhen Yang2, Zheng Li2, Kevin Burgess1.
Abstract
Rucaparib-containing fluorescent probes (1-3) inhibit PARP1 in cell models. One of these (1) was tested in a murine model and shown to permeate into implanted intracranial glioblastoma tumors and persist there for at least 24 h.Entities:
Year: 2022 PMID: 35707158 PMCID: PMC9190034 DOI: 10.1021/acsmedchemlett.1c00712
Source DB: PubMed Journal: ACS Med Chem Lett ISSN: 1948-5875 Impact factor: 4.632