Alireza Sanei-Dehkordi1,2, Mahmoud Agholi3, Mahsa Shafiei4, Mahmoud Osanloo5. 1. Department of Medical Entomology and Vector Control, School of Health, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. 2. Infectious and Tropical Diseases Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. 3. Department of Medical Parasitology and Mycology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran. 4. Noncommunicable Disease Research Center, Fasa University of Medical Sciences, Fasa, Iran. 5. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Fasa University of Medical Sciences, Fasa, Iran. m.osanloo@fums.ac.ir.
Abstract
PURPOSE: An attempt was made in the current study to develop a natural mosquito larvicide using nanotechnology. METHODS: Solid lipid nanoparticles (SLNs) containing three essential oils were first prepared using the high-pressure homogenizer. Larvicidal effects of essential oils and the SLNs against Anopheles stephensi were then compared. RESULTS: The size of SLN containing Mentha longifolia, Mentha pulegium, Zataria multiflora essential oil was obtained as 105 ± 7, 210 ± 4, and 137 ± 8 nm. Their zeta potentials were - 7.8, - 4.7, and - 9.7 mV. Besides, their efficacy with LC50 values of 24.79, 5.11, and 9.19 µg/mL was significantly more potent than that of their un-formulated essential oils with LC50 values of 36.2, 27.55, and 33.33 µg/mL. CONCLUSION: SLNs containing M. pulegium with the best efficacy (P < 0.05) could be considered as potent larvicides against other important species of mosquitoes and field trials.
PURPOSE: An attempt was made in the current study to develop a natural mosquito larvicide using nanotechnology. METHODS: Solid lipid nanoparticles (SLNs) containing three essential oils were first prepared using the high-pressure homogenizer. Larvicidal effects of essential oils and the SLNs against Anopheles stephensi were then compared. RESULTS: The size of SLN containing Mentha longifolia, Mentha pulegium, Zataria multiflora essential oil was obtained as 105 ± 7, 210 ± 4, and 137 ± 8 nm. Their zeta potentials were - 7.8, - 4.7, and - 9.7 mV. Besides, their efficacy with LC50 values of 24.79, 5.11, and 9.19 µg/mL was significantly more potent than that of their un-formulated essential oils with LC50 values of 36.2, 27.55, and 33.33 µg/mL. CONCLUSION: SLNs containing M. pulegium with the best efficacy (P < 0.05) could be considered as potent larvicides against other important species of mosquitoes and field trials.
Authors: George Koliopoulos; Danae Pitarokili; Elias Kioulos; Antonios Michaelakis; Olga Tzakou Journal: Parasitol Res Date: 2010-04-20 Impact factor: 2.289
Authors: Michelle L Gatton; Nakul Chitnis; Thomas Churcher; Martin J Donnelly; Azra C Ghani; H Charles J Godfray; Fred Gould; Ian Hastings; John Marshall; Hilary Ranson; Mark Rowland; Jeff Shaman; Steve W Lindsay Journal: Evolution Date: 2013-02-15 Impact factor: 3.694