Literature DB >> 35702703

Extracellular Vesicles That Herald the Scarcity of Oxygen.

Sekyung Oh1, Sang-Ho Kwon2.   

Abstract

The natural, membrane-bound nanoscale particles, called extracellular vesicles (EVs) have emerged as an effective, versatile vehicle to transport desired drugs specifically to injury sites. Heralding the presence of the scarcity of oxygen, EVs produced from the cells upregulating the expression of the critical transcriptional regulator of hypoxia, HIF-1, can induce a response in ischemia-reperfusion-damaged cells to ameliorate renal tubular injury and inflammation.
Copyright © 2022 by S. Karger AG, Basel.

Entities:  

Keywords:  Exosomes; Extracellular vesicles; Hypoxia; Ischemia; Kidney injury

Year:  2022        PMID： 35702703      PMCID： PMC9149483          DOI： 10.1159/000524423

Source DB:  PubMed          Journal:  Kidney Dis (Basel)        ISSN： 2296-9357


  22 in total

Review 1.  Extracellular vesicles as drug delivery systems: Why and how?

Authors:  Omnia M Elsharkasy; Joel Z Nordin; Daniel W Hagey; Olivier G de Jong; Raymond M Schiffelers; Samir El Andaloussi; Pieter Vader
Journal:  Adv Drug Deliv Rev       Date:  2020-04-16       Impact factor: 15.470

2.  Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.

Authors:  P Jaakkola; D R Mole; Y M Tian; M I Wilson; J Gielbert; S J Gaskell; A von Kriegsheim; H F Hebestreit; M Mukherji; C J Schofield; P H Maxwell; C W Pugh; P J Ratcliffe
Journal:  Science       Date:  2001-04-05       Impact factor: 47.728

Review 3.  Ischemic Preconditioning of the Kidney.

Authors:  E Yu Plotnikov
Journal:  Bull Exp Biol Med       Date:  2021-10-07       Impact factor: 0.804

4.  Therapeutic Effect of Extracellular Vesicles Derived from HIF Prolyl Hydroxylase Domain Enzyme Inhibitor-Treated Cells on Renal Ischemia/Reperfusion Injury.

Authors:  Zhao-Ying Ding; Tao-Tao Tang; Zuo-Lin Li; Jing-Yuan Cao; Lin-Li Lv; Yi Wen; Bin Wang; Bi-Cheng Liu
Journal:  Kidney Dis (Basel)       Date:  2022-03-25

Review 5.  Hypoxia and the HIF system in kidney disease.

Authors:  Masaomi Nangaku; Kai-Uwe Eckardt
Journal:  J Mol Med (Berl)       Date:  2007-11-20       Impact factor: 4.599

Review 6.  Hypoxia-inducible factors in the kidney.

Authors:  Volker H Haase
Journal:  Am J Physiol Renal Physiol       Date:  2006-03-22

Review 7.  Oxidative stress and autophagy: crucial modulators of kidney injury.

Authors:  Angara Sureshbabu; Stefan W Ryter; Mary E Choi
Journal:  Redox Biol       Date:  2015-01-13       Impact factor: 11.799

Review 8.  Maintenance of redox homeostasis by hypoxia-inducible factors.

Authors:  Debangshu Samanta; Gregg L Semenza
Journal:  Redox Biol       Date:  2017-05-31       Impact factor: 11.799

9.  Delayed Remote Ischemic Preconditioning ConfersRenoprotection against Septic Acute Kidney Injury via Exosomal miR-21.

Authors:  Tianyi Pan; Ping Jia; Nan Chen; Yi Fang; Yiran Liang; Man Guo; Xiaoqiang Ding
Journal:  Theranostics       Date:  2019-01-01       Impact factor: 11.556

10.  Kim-1 Targeted Extracellular Vesicles: A New Therapeutic Platform for RNAi to Treat AKI.

Authors:  Tao-Tao Tang; Bin Wang; Zuo-Lin Li; Yi Wen; Song-Tao Feng; Min Wu; Dan Liu; Jing-Yuan Cao; Qing Yin; Di Yin; Yu-Qi Fu; Yue-Ming Gao; Zhao-Ying Ding; Jing-Yi Qian; Qiu-Li Wu; Lin-Li Lv; Bi-Cheng Liu
Journal:  J Am Soc Nephrol       Date:  2021-06-14       Impact factor: 14.978
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